ArticleGlobal health action2024
Alcohol consumption and allergic diseases: Mendelian randomization evidence from China.
Article in Global health action, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Reducing alcohol consumption among adolescents: intervention strategies by Chinese healthcare professionals.Frontiers in public health · 2025Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of allergic diseases in China has risen significantly over the past decades, affecting the quality of life for approximately 40% of the population.
objectivesThis study aimed to integrate survey and genomic data to explore the potential causal relationship between alcohol consumption and allergic diseases.
methodIn collaboration with a leading genetic testing company in China, we collected data on 3,041 participants via an online survey between December 2018 and October 2019. A Mendelian Randomization (MR) design was employed in data analysis, leveraging the random allocation of genes at meiosis in humans to create instrumental variables for alcohol intake. This method was used to estimate the causal effect of alcohol consumption on the incidence of allergic diseases.
resultsWhile ordinary least-squares estimates showed a negative association between alcohol drinking and the risk of self-reported allergic diseases, MR estimates suggest that higher alcohol consumption increased the risks of allergy in certain subgroups. Specifically, predicted drinking [b = 0.445,
conclusionHigher alcohol intake is causally associated with a higher risk of allergic diseases in Chinese women but not men.
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