Evidence map›Paper›PMID 39838730›Full record

ReviewMacromolecular bioscience2025

Polymeric Nanoarchitectures: Advanced Cargo Systems for Biological Applications.

Yingtong Luo, Yudong Li, Loai K E A Abdelmohsen, Jingxin Shao, Jan C M van Hest

Abstract readReview
In one paragraph

Review in Macromolecular bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingtong LuoBio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, 5600 MB, The Netherlands.
Yudong LiBio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, 5600 MB, The Netherlands.
Loai K E A AbdelmohsenBio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, 5600 MB, The Netherlands.
Jingxin ShaoBio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, 5600 MB, The Netherlands.
Jan C M van HestBio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, 5600 MB, The Netherlands.ORCID 0000-0001-7973-2404

Funding

China Scholarship CouncilDutch Ministry of Education, Culture, and ScienceMinisterie van Onderwijs, Cultuur en Wetenschap Spinoza premium SPI 71-259
6 · The paper itself

Abstract

Polymeric nanoarchitectures are crafted from amphiphilic block copolymers through a meticulous self-assembly process. The composition of these block copolymers is finely adjustable, bestowing precise control over the characteristics and properties of the resultant polymeric assemblies. These nanoparticles have garnered significant attention, particularly in the realm of biological sciences, owing to their biocompatibility, favorable pharmacokinetics, and facile chemically modifiable nature. Among the myriad of polymeric nanoarchitectures, micelles and polymersomes stand out as frontrunners, exhibiting much potential as cargo carrier systems for diverse bio-applications. This review elucidates the design strategies employed for amphiphilic block copolymers and their resultant assemblies, specifically focusing on micelles and polymersomes. Subsequently, it discusses their wide-ranging bio-applications, spanning from drug delivery and diagnostics to bioimaging and artificial cell applications. Finally, a reflective analysis will be provided, highlighting the current landscape of polymeric cargo carriers, and discussing the opportunities and challenges that lie ahead. With this review, it is aimed to summarize the recent advances in polymeric assemblies and their applications in the biomedical field.

Indexed as

Drug CarriersDrug Delivery SystemsNanoparticlesPolymersAnimalsHumansMicellesDrug CarriersMicellesPolymersamphiphilic block copolymersbio‐applicationsmicellespolymersomesself‐assembly

Identifiers

PMID39838730
PMCPMC12080326

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.