Evidence map›Paper›PMID 39838351›Full record

ArticleBMC ophthalmology2025

Coats-Like reaction post-vitreoretinal surgery for PDR managed with laser photocoagulation and adjunctive intravitreal steroids- a case report.

Kanika Godani, Shruti Vidyasagar, Preksha Biradar, Vishma Prabhu, Prathiba Hande, Priyanka Gandhi, Rupal Kathare, Jay Chhablani, Ramesh Venkatesh

Abstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kanika GodaniDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Shruti VidyasagarDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Preksha BiradarDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Vishma PrabhuDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Prathiba HandeDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Priyanka GandhiDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Rupal KathareDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Jay ChhablaniDepartment of Medical Retina and Vitreoretinal Surgery, University of Pittsburgh School of Medicine, 203 Lothrop Street, Suite 800, Pittsburg, PA, 15213, USA.
Ramesh VenkateshDept. of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India. vramesh80@yahoo.com.ORCID http://orcid.org/0000-0002-4479-9390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a rare case of a Coats-like response developing after vitreoretinal surgery for proliferative diabetic retinopathy (PDR) and its successful management with retinal laser photocoagulation and adjunctive intravitreal steroids. CASE DESCRIPTION: A 52-year-old woman with a five-year history of type 2 diabetes mellitus and hypertension presented with decreased vision in the left eye (counting fingers at 1 m). Examination revealed high-risk PDR in both eyes, with a subtotal macula-off combined retinal detachment in the left eye. The patient underwent pan retinal photocoagulation for the right eye and vitreoretinal surgery with silicone oil tamponade for the left eye. Postoperatively, the retina remained attached, but progressive increase in hard exudates in the inferotemporal quadrant was noted in the left eye. Wide-field fluorescein angiography showed temporal capillary dropout and leakage corresponding to the exudates, consistent with a Coats-like response.

resultsSilicone oil removal combined with targeted endolaser photocoagulation and intravitreal triamcinolone acetonide injection resulted in a complete resolution of the subretinal lipid exudation. Two weeks postoperatively, the retina remained well-attached, but best-corrected visual acuity declined to 6/60 due to posterior subcapsular cataract progression. Optical coherence tomography confirmed the resolution of subretinal lipid exudation, and the patient was advised to undergo cataract surgery.

conclusionThis case highlights the occurrence of a Coats-like response following vitreoretinal surgery for PDR, potentially triggered by retinal ischemia and surgical inflammation. Timely intervention with laser photocoagulation, and adjunctive intravitreal corticosteroids can effectively manage such responses.

Indexed as

Diabetic RetinopathyGlucocorticoidsLaser CoagulationPostoperative ComplicationsTriamcinolone AcetonideVitreoretinal SurgeryFemaleFluorescein AngiographyHumansIntravitreal InjectionsMiddle AgedTomography, Optical CoherenceVisual AcuityGlucocorticoidsTriamcinolone AcetonideCoats-like responseProliferative diabetic retinopathy (PDR)Retinal ischemiaRetinal laser photocoagulationVitreoretinal surgery

Identifiers

PMID39838351
PMCPMC11748534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.