Evidence map›Paper›PMID 39838260›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2025

MT1/cAMP/PKA Pathway in Melatonin-Regulated Sperm Capacitation.

Tongjuan Niu, Di Zhang, Guobin Qiu, Bin Li, Sheng Cui

Abstract read
PubMed Publisher
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tongjuan NiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
Di ZhangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
Guobin QiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
Bin LiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, China.
Sheng CuiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu, China. cuisheng@yzu.edu.cn.ORCID 0000-0002-3826-3768

Funding

Natural Science Foundation of China 32130098
6 · The paper itself

Abstract

Melatonin is mainly synthesized and secreted by pineal gland, and plays multiple functions, including its regulating effects on reproductive processes. Sperm capacitation is necessary for fertilization, but the effect of melatonin on mouse sperm capacitation remains to be elucidated. We thus investigated the roles of melatonin on capacitation by culturing the sperms from mouse cauda epididymis in the medium with different doses of melatonin. The results showed that 10

Indexed as

Cyclic AMPCyclic AMP-Dependent Protein KinasesMelatoninReceptor, Melatonin, MT1Signal TransductionSpermatozoaSperm CapacitationAnimalsFemaleMaleMicePhosphorylationCyclic AMPCyclic AMP-Dependent Protein KinasesMelatoninReceptor, Melatonin, MT1CAMP/PKAMelatoninMT1Sperm capacitation

Identifiers

PMID39838260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.