Evidence map›Paper›PMID 39838177›Full record

ArticleScientific reports2025

Integrated analysis of genetic, proteinic, and metabolomic alterations in Behcet's disease.

Yanlin Pu, Jing Liang, Yao Wang, Wanyun Zhang, Chuiren Zhou, Ju Shao, Jin Hu, Minghui Chen, Yunjie Shi, Yongdan Mao and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Behçet's Syndrome.Current rheumatology reports · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Neutrophils: emerging perspectives on the pathogenesis of oral mucosal diseases.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yanlin Pu *Department of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Jing Liang *Department of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Yao Wang *Chongqing Key Laboratory of Ophthalmology, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing Eye Institute, Chongqing, China.
Wanyun ZhangChongqing Key Laboratory of Ophthalmology, Chongqing Branch (Municipality Division) of National Clinical Research Center for Ocular Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing Eye Institute, Chongqing, China.
Chuiren ZhouDepartment of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Ju ShaoDepartment of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Jin HuDepartment of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Minghui ChenDepartment of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Yunjie ShiDepartment of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Yongdan MaoDepartment of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760.
Zhijun ChenDepartment of Ophthalmology, Bishan hospital of Chongqing medical university, Bishan Hospital of Chongqing, Chongqing, China, 402760. 1093284845@qq.com.

Funding

China Postdoctoral Science Foundation 2024MD754020Natural Science Foundation of Chongqing Municipality CSTB2024NSCQ-MSX0950
6 · The paper itself

Abstract

Numerous studies have investigated the alterations of genes, proteins, and metabolites in Behcet's disease (BD). By far, little is known about the depiction of panoramic changes underlying this disease. This study purposed to assess the consistently dysregulated genes, proteins, and metabolites in BD across publications using the vote-counting approach. This study was based on 745 studies that identified a collection of 2354 differential molecules with 3574 molecule entries in blood, peripheral blood mononuclear cells, CD4

Indexed as

Behcet SyndromeCD4-Positive T-LymphocytesCytokinesHumansInterferon-gammaLeukocytes, MononuclearMaleMetabolomicsTh1 CellsCytokinesInterferon-gammaBehcet’s diseaseUveitisVote-counting analysis

Identifiers

PMID39838177
PMCPMC11751112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.