Evidence map›Paper›PMID 39838058›Full record

ArticleScientific reports2025

Characterization of some selected macroalgae extracts and assessment of their insecticidal and genotoxicity in Culex pipiens L. mosquito larvae.

Dina A Refaay, Mostafa M El-Sheekh, Yasmin M Heikal, Ahmed A Rashed

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Current research in insect science · 2026
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dina A RefaayBotany Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt. dalirefy@mans.edu.eg.
Mostafa M El-SheekhBotany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Yasmin M HeikalBotany Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Ahmed A RashedEconomic Entomology Department, Faculty of Agriculture, Mansoura University, Mansoura, 35516, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continual use of synthetic insecticides to control mosquito larvae has severe implications for human health and the ecosystem, highlighting the need for alternative natural insecticides. Macroalgae may be a good alternative because of their biologically active metabolites with distinctive chemical structures that have been reported for their insecticidal properties. The study aimed to investigate the potential of different extracts from Jania rubens (Linnaeus) J.V.Lamouroux and Colpomenia sinuosa (Mertens ex Roth) Derbès & Solier as genotoxic and larvicidal agents against Culex pipiens Linnaeus larvae. The algae thallus was subjected to extraction using methanol, acetone, and methylene chloride. The phytochemical composition was quantified. The larvicidal activity of the different algae extracts was assessed against the third instar larvae of Culex pipiens. Genotoxic evaluation through comet assays and compound characterization by GC/MS was done. The results demonstrated that J. rubens methylene chloride extract exhibited the highest contents of phenolics, alkaloids, flavonoids, terpenoids, and tannins while C. sinuosa methanol extract demonstrated the highest levels of flavonoids, alkaloids, phenolics, and saponins. The larvicidal activity results revealed that J. rubens methylene chloride extract was the most toxic for C. pipiens larvae with LC

Indexed as

CulexInsecticidesPlant ExtractsSeaweedAnimalsLarvaInsecticidesPlant ExtractsAlgal bioinsecticideColpomenia sinuosaComet assayJania rubensLarvicidal activityPhytochemicals

Identifiers

PMID39838058
PMCPMC11751296

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.