Evidence map›Paper›PMID 39837985›Full record

ArticleCommunications medicine2025

Modeling of magnetic vestibular stimulation experienced during high-field clinical MRI.

Ismael Arán-Tapia, Vicente Pérez-Muñuzuri, Alberto P Muñuzuri, Andrés Soto-Varela, Jorge Otero-Millan, Dale C Roberts, Bryan K Ward

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ismael Arán-TapiaGroup of Non-Linear Physics, University of Santiago de Compostela, Santiago de Compostela, Spain. ismaelaran.tapia@usc.es.ORCID http://orcid.org/0000-0002-2881-2807
Vicente Pérez-MuñuzuriGroup of Non-Linear Physics, University of Santiago de Compostela, Santiago de Compostela, Spain.
Alberto P MuñuzuriGroup of Non-Linear Physics, University of Santiago de Compostela, Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0002-0579-9347
Andrés Soto-VarelaDivision of Neurotology, Department of Otorhinolaryngology, Complexo Hospitalario Universitario, Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0001-6763-329X
Jorge Otero-MillanSchool of Optometry, The University of California, Berkeley, CA, USA.
Dale C RobertsDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bryan K WardDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. bward15@jh.edu.ORCID http://orcid.org/0000-0001-5201-6117

Funding

HIGH FIELD MRI AND THE LABYRINTH: VESTIBULAR STIMULATION AND NEW IMAGING TECHNIQUESK23DC018302 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI WARD, BRYAN KEVIN · 2021 to 2025
$991k
Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) PI23/00248NIDCD NIH HHS K23 DC018302U.S. Department of Health & Human Services | National Institutes of Health (NIH) K23DC018302
6 · The paper itself

Abstract

backgroundHigh-field magnetic resonance imaging (MRI) is a powerful diagnostic tool but can induce unintended physiological effects, such as nystagmus and dizziness, potentially compromising the comfort and safety of individuals undergoing imaging. These effects likely result from the Lorentz force, which arises from the interaction between the MRI's static magnetic field and electrical currents in the inner ear. Yet, the Lorentz force hypothesis fails to explain observed eye movement patterns in healthy adults fully. This study explores these effects and tests whether the Lorentz force hypothesis adequately explains magnetic vestibular stimulation.

methodsWe developed a mathematical model integrating computational fluid dynamics, fluid-structure interaction solvers, and magnetohydrodynamic equations to simulate the biomechanical response of the cristae ampullares. Using high-resolution micro-CT data of the human membranous labyrinth, we ensured anatomical accuracy. Experimental validation involved measuring horizontal, vertical, and torsional slow-phase eye movements in healthy subjects exposed to varying magnetic field intensities and head positions.

resultsOur model accurately replicates observed nystagmus patterns, predicting slow-phase eye velocities that match experimental data. Results indicate that Lorentz force-induced stimulation of individual cupulae explains variability in eye movements across different magnetic field intensities and head orientations.

conclusionsThis study empirically supports the Lorentz force hypothesis as a valid explanation for magnetic vestibular stimulation, offering new insights into the effects of high-field MRI on the vestibular system. These findings provide a foundation for future research and improved clinical practices.

Identifiers

PMID39837985
PMCPMC11751175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.