Evidence map›Paper›PMID 39837780›Full record

ReviewOrthopaedic surgery2025

Analysis of Animal Models of Traumatic Osteonecrosis of the Femoral Head Based on Blood Supply: A Literature Review.

Linbao Wang, Yunzhuan Luo, Xing Qiu, Liangliang Cheng, Kaiming Ma, Jianchen Guan, Yuchen Liu, Jiawei Ying, Dewei Zhao

Abstract readReview
In one paragraph

Review in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Linbao WangDepartment of Orthopaedic, Affiliated ZhongShan Hospital of Dalian University, Dalian, China.
Yunzhuan LuoDepartment of Orthopaedic, Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Xing QiuDepartment of Orthopaedic, Affiliated ZhongShan Hospital of Dalian University, Dalian, China.ORCID https://orcid.org/0000-0002-2479-7777
Liangliang ChengDepartment of Orthopaedic, Affiliated ZhongShan Hospital of Dalian University, Dalian, China.
Kaiming MaDepartment of Orthopaedic, Affiliated ZhongShan Hospital of Dalian University, Dalian, China.
Jianchen GuanDepartment of Orthopaedic, Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Yuchen LiuDepartment of Orthopaedic, Affiliated ZhongShan Hospital of Dalian University, Dalian, China.ORCID https://orcid.org/0009-0006-7325-648X
Jiawei YingDepartment of Orthopaedic, Affiliated ZhongShan Hospital of Dalian University, Dalian, China.ORCID https://orcid.org/0000-0001-7427-1047
Dewei ZhaoDepartment of Orthopaedic, Affiliated ZhongShan Hospital of Dalian University, Dalian, China.ORCID https://orcid.org/0000-0001-8611-0558

Funding

Dalian Key Medical Specialty Contruction Fund Project Peak Plan-2021-243Dalian Science and Technology Innovation Fund Project 2023JJ13SN042
6 · The paper itself

Abstract

Traumatic osteonecrosis of the femoral head (TONFH) refers to ischemic osteonecrosis is resulting from an acute mechanical interruption of the blood supply to the femoral head. The early diagnosis and optimal treatment have been central focuses of research and continue to undergo improvement. Reliable animal models are essential for advancing research into the treatment of the disease. This review aims to provide a comprehensive overview of tetrapod models (rats, rabbits, dogs, and sheep) and bipod models (emus, ostriches), as well as various modeling methods (traumatic hip dislocation, dissection of the round ligament and ligature of the femoral neck, femoral neck fracture (FNF), reduction and internal fixation after femoral neck fracture, and highly selective disruption of the anterior-superior retinacular vessels). This review examines the advantages, disadvantages, and applicability of each model. Based on blood flow analysis, it proposes a more reliable direction for TONFH modeling: simulating partial blood flow injury in the context of FNF.

Indexed as

Disease Models, AnimalFemur HeadFemur Head NecrosisAnimalsDogsRabbitsanimal modelfemoral neck fractureinflammatory responseretinacular vesselstraumatic osteonecrosis of the femoral head

Identifiers

PMID39837780
PMCPMC11872375

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.