ArticleBMJ supportive & palliative care2025
Rational use of human albumin: plan-do-check-act cycle in clinical practice.
Article in BMJ supportive & palliative care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
objectiveImproper use of human albumin (HA) is now common in clinical settings. This study aims to explore the feasibility of the plan-do-check-act (PDCA) cycle in promoting the rational use of HA.
methodsThe differences between the control and observation groups (after the PDCA cycle) in terms of serum albumin detection rate, serum albumin values, HA usage, and rationality were analysed and compared using a before-and-after control method.
resultsA total of 372 patients were recruited, including 186 in each of the control and observation groups. On comparison, it was observed that the overall use of HA improved after the PDCA cycle compared with the preintervention period, and the rational rate of HA prescriptions increased from 68.3% to 96.2%. The serum albumin detection rate before applying for HA increased from 83.9% to 98.9%, and the median values decreased from 26.7 (22.8-30.9) g/L to 24.7 (22.7-27.2) g/L. Regarding the use of HA, the median amount of HA used was reduced by 20 g compared with the preintervention period, meanwhile, the median duration was shortened by 2 days.
conclusionThe PDCA cycle is desirable when employed to promote the rational use of HA.
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