Evidence map›Paper›PMID 39837517›Full record

ArticleProceedings. Biological sciences2025

Early prenatal but not postnatal glucocorticoid exposure is associated with enhanced HPA axis activity into adulthood in a wild primate.

Simone Anzà, Michael Heistermann, Julia Ostner, Oliver Schülke

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simone AnzàDepartment of Medicine, Infectious Diseases Division, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0001-9498-6621
Michael HeistermannEndocrinology Laboratory, German Primate Center, Leibniz Institute for Primate Research, Goettingen, Germany.
Julia OstnerBehavioral Ecology Department, University of Goettingen, Goettingen, Germany.ORCID 0000-0001-6871-9976
Oliver SchülkeBehavioral Ecology Department, University of Goettingen, Goettingen, Germany.ORCID 0000-0003-0028-9425

Funding

Deutsche Forschungsgemeinschaft
6 · The paper itself

Abstract

The hypothalamic-pituitary-adrenal (HPA) axis plays a dual role in the biology of developmental plasticity in mammals, including humans-HPA axis activity not only provides the input for, but is also a target of, offspring developmental plasticity. To investigate the understudied effects of exposure timing, this study quantified maternal HPA axis activity during each half of gestation as well as during early lactation and assessed its effect on offspring HPA axis activity in a cross-sectional sample of infant, juvenile and adult Assamese macaques (

Indexed as

GlucocorticoidsHypothalamo-Hypophyseal SystemMacacaPituitary-Adrenal SystemAnimalsFecesFemaleLactationMalePregnancyPrenatal Exposure Delayed EffectsGlucocorticoidsdevelopmental plasticitymaternal effectssensitive periodsstress response

Identifiers

PMID39837517
PMCPMC11750380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.