ArticleThe Journal of clinical endocrinology and metabolism2025
Life With Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency: Challenges and Burdens.
Article in The Journal of clinical endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Exploring Factors Associated With Parental Acceptance-Rejection Among Parents of Children With Congenital Adrenal Hyperplasia in Central Java, Indonesia.Journal of genetic counseling · 2026Article
- Glucocorticoid reduction after starting crinecerfont in adult patients with classic CAH: practical perspectives.The Journal of clinical endocrinology and metabolism · 2026Article
- Living with congenital adrenal hyperplasia: insights on quality of life.Frontiers in endocrinology · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextCongenital adrenal hyperplasia (CAH) is an autosomal recessive genetic condition requiring daily medication(s) and attention to details. In addition to daily medications and regular visits with healthcare providers, families may live with perpetual angst regarding unpredictable occurrences of acute adrenal insufficiency. Despite numerous barriers and challenges imposed by this chronic condition, caregivers and healthcare professionals can empower our patients to achieve a good quality of life. EVIDENCE SYNTHESIS: CAH is a global condition for which access to health care widely varies depending on local resources. Major treatment aims include good health, good quality of life, and achievement of personal goals for affected persons. To achieve these aims, patients, caregivers, and healthcare professionals interact to promote health maintenance and encourage positive outcomes for individuals with CAH. This article describes aspects of daily living with CAH through the perspective of 1 family and their healthcare team living in the United States. A young adult patient, nurse educator, and physicians provide their perspectives regarding patient health care, general well-being, and safety emphasizing that patients with CAH can thrive. Nevertheless, remembering and recognizing that many individuals with CAH live in areas with limited resources and enduring sociocultural barriers is essential.
conclusionWith access to knowledgeable healthcare providers, sufficient resources, and psychosocial support, "children with CAH can thrive and live normal lives." The future challenge is securing mechanisms to decrease the financial, sociocultural, and health access barriers in other communities throughout the world.
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Registered trials
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