Evidence map›Paper›PMID 39836442›Full record

ReviewEcology letters2025

Causal Inference With Observational Data and Unobserved Confounding Variables.

Jarrett E K Byrnes, Laura E Dee

Abstract readReview
In one paragraph

Review in Ecology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Riparian vegetation reduces coastal turbidity.Communications sustainability · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jarrett E K ByrnesDepartment of Biology, University of Massachusetts Boston, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-9791-9472
Laura E DeeDepartment of Ecology and Evolutionary Biology, University of Colorado Boulder, Boulder, Colorado, USA.ORCID https://orcid.org/0000-0003-0471-1371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experiments have long been the gold standard for causal inference in Ecology. As Ecology tackles progressively larger problems, however, we are moving beyond the scales at which randomised controlled experiments are feasible. To answer causal questions at scale, we need to also use observational data -something Ecologists tend to view with great scepticism. The major challenge using observational data for causal inference is confounding variables: variables affecting both a causal variable and response of interest. Unmeasured confounders-known or unknown-lead to statistical bias, creating spurious correlations and masking true causal relationships. To combat this omitted variable bias, other disciplines have developed rigorous approaches for causal inference from observational data that flexibly control for broad suites of confounding variables. We show how ecologists can harness some of these methods-causal diagrams to identify confounders coupled with nested sampling and statistical designs-to reduce risks of omitted variable bias. Using an example of estimating warming effects on snails, we show how current methods in Ecology (e.g., mixed models) produce incorrect inferences due to omitted variable bias and how alternative methods can eliminate it, improving causal inferences with weaker assumptions. Our goal is to expand tools for causal inference using observational and imperfect experimental data in Ecology.

Indexed as

EcologyObservational Studies as TopicAnimalsBiasCausalityModels, BiologicalResearch DesignSnailscausal inferencecausalitycorrelated random effectsendogeneitymixed modelsobservational dataomitted variable biaspanel regressionstructural causal model

Identifiers

PMID39836442
PMCPMC11750058

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.