Evidence map›Paper›PMID 39836311›Full record

ArticleMikrochimica acta2025

Smartphone-based non-invasive detection of salivary uric acid based on the fluorescence quenching of gleditsia sinensis carbon dots.

Yujuan Xiang, Hongpeng Yu, Kegang Wu, Ziting Quan, Dong He, Cansheng Ou, Xianghua Chai, Yinglin Liang, Xuejuan Duan, Xiangyu Zhang and 2 more

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yujuan XiangSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, No. 100 Waihuan Xi Road, Panyu District, Guangzhou, 510006, People's Republic of China.
Hongpeng YuGuangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center, Guangdong University of Technology, Jieyang City, 522000, People's Republic of China.
Kegang WuGuangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center, Guangdong University of Technology, Jieyang City, 522000, People's Republic of China.
Ziting QuanSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, No. 100 Waihuan Xi Road, Panyu District, Guangzhou, 510006, People's Republic of China.
Dong HeGuangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center, Guangdong University of Technology, Jieyang City, 522000, People's Republic of China. hedong86284116@163.com.
Cansheng OuSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, No. 100 Waihuan Xi Road, Panyu District, Guangzhou, 510006, People's Republic of China.
Xianghua ChaiSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, No. 100 Waihuan Xi Road, Panyu District, Guangzhou, 510006, People's Republic of China.
Yinglin LiangSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, No. 100 Waihuan Xi Road, Panyu District, Guangzhou, 510006, People's Republic of China.
Xuejuan DuanSchool of Chemical Engineering and Light Industry, Guangdong University of Technology, No. 100 Waihuan Xi Road, Panyu District, Guangzhou, 510006, People's Republic of China.
Xiangyu ZhangInstitute of Traditional Chinese Medicine, Guizhou Province, Bijie City, 551700, China.
Qin ZhaInstitute of Traditional Chinese Medicine, Guizhou Province, Bijie City, 551700, China.
Wei XieGuizhou Province, Qianzhi Mingguang Soaphorn Rice Processing Base, Zhijin County, Maochang Town, Bijie CityBijie City, 552103, China.

Funding

Science & Technology Planning Project of Guangzhou City 202206010181，2024E04J0379，20210300007Science and technology plan project of Heyuan City 220705101471437
6 · The paper itself

Abstract

A smartphone-based non-invasive method was developed for salivary uric acid detection using Gleditsia Sinensis carbon dots (GS-CDs). The GS-CDs synthesized by the one-pot hydrothermal method emitted blue fluorescence at a maximum excitation wavelength of 350 nm and had good fluorescence stability in the presence of different ions, while showing selectivity to uric acid solution. The ability of uric acid (UA) to quench the fluorescent substances present in the GS-CDs, was confirmed through HPLC-FLD and LC-MS, FTIR and XPS. The results showed that UA reacted with GS-CDs, with a decrease in hydroxyl groups and the formation of carboxyl groups. The fluorescence quenching suggested a possible dynamic quenching mechanism. In addition, a smartphone-based non-invasive detection method was developed for the detection of salivary UA levels, which reflects blood UA levels. This study provides a new perspective on the utilization of GS shells and advances the development of non-invasive testing for UA.

Indexed as

CarbonQuantum DotsSalivaSmartphoneUric AcidAnimalsFluorescenceFluorescent DyesHumansLimit of DetectionSpectrometry, FluorescenceCarbonFluorescent DyesUric AcidFluorescenceGleditsia Sinensis Carbon DotsNon-invasiveSalivary uric acidSmartphone-based color image detection

Identifiers

PMID39836311

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