Evidence map›Paper›PMID 39836282›Full record

ArticleMolecular biology reports2025

Evaluation of variations in predominant gut microbiota members in inflammatory bowel disease using real-time PCR.

Mina Tasoujlu, Yaeghob Sharifi, Maryam Ghahremani, Kasra Alizadeh, Farhad Babaie, Mohammadreza Mohammad Hosseiniazar

Abstract read
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In one paragraph

Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nutrients · 2026
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mina TasoujluCellular and Molecular Research Center, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Yaeghob SharifiCellular and Molecular Research Center, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran. ya.sharifi@gmail.com.
Maryam GhahremaniDepartment of Microbiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Kasra AlizadehDepartment of Microbiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Farhad BabaieDepartment of Immunology and Genetics, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Mohammadreza Mohammad HosseiniazarDepartment of Internal Medicine, Faculty of Medicine, Urmia University of Medical Sciences, Imam Khomeini Hospital, Urmia, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory Bowel Disease (IBD) is a persistent ailment that impacts many individuals worldwide. The interaction between the immune system and gut microbiome is thought to influence IBD development. This study aimed to assess some microbiota in IBD patients compared to healthy individuals. The investigation involved a selected group of twenty patients suffering from IBD and an equal number of healthy participants. Stool specimens were obtained and analyzed for Lactobacillus, Bifidobacterium, Bacteroides, Clostridium leptum, Akkermansia muciniphila, Fusobacterium and Enterobacteriaceae using real-time PCR. The findings indicated significantly higher levels of Bifidobacterium in IBD patients (Pv = 0.009) and lower levels of A. muciniphila (Pv = 0.003) healthy individuals. Other bacteria tested did not show significant differences. The study suggests that the progression of IBD patients could be influenced by the rising of Bifidobacterium and the declining of A. muciniphila. Targeting these bacteria could lead to improved treatments and quality of life for those with IBD.

Indexed as

AkkermansiaFecesGastrointestinal MicrobiomeInflammatory Bowel DiseasesReal-Time Polymerase Chain ReactionAdultBacteriaBifidobacteriumCase-Control StudiesEnterobacteriaceaeFemaleHumansLactobacillusMaleMiddle AgedBacteroidesBifidobacteriumDysbiosisGut microbiotaInflammatory bowel diseaseLactobacillus

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.