ArticleInternational urogynecology journal2025
Global Trends in Prevalence and Future Projections of Pelvic Organ Prolapse: A 30-year Epidemiological Study.
Article in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Thrombospondin-1 as a Mechanosensitive Matrix Protein Driving Fibroblast Senescence: A Novel Pathogenic Target for Pelvic Organ Prolapse.International urogynecology journal · 2026Article
- Multimodal Prediction Model for Postoperative Voiding Dysfunction After Pelvic Organ Prolapse Surgery.International urogynecology journal · 2026Article
- A Retrospective Cohort Study of Bilateral Sacrospinous Ligament Fixation Over a Decade of Clinical Experience.International urogynecology journal · 2026Article
- Multidimensional regulation of estrogen signaling in pelvic floor connective tissue homeostasis and remodeling.Frontiers in immunology · 2026Review
- Single-cell and spatial multi-omics reveal estrogen-mediated vaginal wall microenvironment remodeling and a perivascular reparative niche in postmenopausal pelvic organ prolapse.Frontiers in immunology · 2026Article
- Anterior-Only Sacrocolpopexy Complicated by Obstructive Enterocele: Should Both Compartments Always Be Repaired?Cureus · 2025Article
- Pelvic Organ Prolapse: Current Challenges and Future Perspectives.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPelvic organ prolapse (POP) is a widespread disease in women. Despite its significant prevalence, there is a lack of comprehensive global studies, emphasizing the urgent need for tailored prevention and treatment approaches. This study aims to examine the global burden of POP from 1990 to 2021 and project future trends using the GBD data.
methodsData were collected from the GBD 2021 database. A Bayesian age-period-cohort (BAPC) model was used to analyze the trends and predict future burden, with age-standardized prevalence rate (ASPR) and years lived with disability (YLD) as key metrics.
resultsIn 2021, the global ASPR and age-standardized YLD rate of POP were 2769.4 (95% UI 2299.2-3298.2) and 8.5 (95% UI 4.1-16.2) per 100,000 people, respectively. Both ASPR and YLD rate decreased between 1990 and 2021. The burden of POP is highest in low-SDI regions. The global prevalence of POP was highest in the 80+ age group, while the absolute number of cases reached its peak in the 55-59 age group. By 2036, the global population of POP patients will reach 156 million. Additionally, both the ASPR and AS-YLD rates of POP will continue to decline over the next 15 years.
conclusionWhile the global burden of POP decreased between 1990 and 2021, ASPRs in regions with low SDI remained high. With the gradual aging population, POP will continue to pose a significant burden on women's health and the social economy in the future. Strengthening global surveillance and prevention efforts for POP remains a critical challenge.
Indexed as
Identifiers
39836174What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.