Evidence map›Paper›PMID 39836064›Full record

ArticleRedox report : communications in free radical research2025

Non-invasive electron paramagnetic resonance imaging detects tumor redox imbalance induced by ferroptosis.

Kazuhiro Kato, Hironobu Yasui, Hideo Sato-Akaba, Miho C Emoto, Hirotada G Fujii, Maciej M Kmiec, Periannan Kuppusamy, Masaki Nagane, Tadashi Yamashita, Osamu Inanami

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Redox report : communications in free radical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Reconfigurable animal bed-EPR resonator assembly for multimodal co-registration.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  3. Advances in redox imaging for cancer diagnosis and therapy.Journal of clinical biochemistry and nutrition · 2026
    Article
  4. Review
  5. Computationally efficient 4D spectral-spatial EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kazuhiro KatoLaboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Hironobu YasuiLaboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.ORCID 0000-0002-6757-1110
Hideo Sato-AkabaDepartment of Electrical and Electronic Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, Hamamatsu, Japan.
Miho C EmotoDepartment of Clinical Laboratory Science, School of Medical Technology, Health Sciences University of Hokkaido, Sapporo, Japan.
Hirotada G FujiiAdvanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari, Japan.
Maciej M KmiecDepartments of Radiology and Radiation Oncology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.
Periannan KuppusamyDepartments of Radiology and Radiation Oncology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.
Masaki NaganeLaboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Sagamihara, Japan.
Tadashi YamashitaLaboratory of Biochemistry, School of Veterinary Medicine, Azabu University, Sagamihara, Japan.
Osamu InanamiLaboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting ferroptosis, cell death caused by the iron-dependent accumulation of lipid peroxides, and disruption of the redox balance are promising strategies in cancer therapy owing to the physiological characteristics of cancer cells. However, the detection of ferroptosis using

Indexed as

FerroptosisNeoplasmsAldehydesAnimalsCell Line, TumorElectron Spin Resonance SpectroscopyFemaleHumansMiceOxidation-ReductionPiperazines4-hydroxy-2-nonenalAldehydeserastinPiperazinescancer therapyElectron paramagnetic resonance imagingferroptosis‌GPX4‌Imidazole ketone erastin‌lipid peroxidationRedox imaging‌tumor redox status

Identifiers

PMID39836064
PMCPMC11753017

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.