Evidence map›Paper›PMID 39835972›Full record

ArticleThe American journal of gastroenterology2025

High Cirrhosis Surgical Volume Centers Have Reduced Postoperative Mortality in Patients With Cirrhosis Undergoing Major Surgery.

Bachir Ghandour, David E Kaplan, Nadim Mahmud

Abstract read
In one paragraph

Article in The American journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bachir GhandourDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
David E KaplanDivision of Gastroenterology and Hepatology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3839-336
Nadim MahmudDivision of Gastroenterology and Hepatology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1889-3954

Funding

Improving Surgical Risk Prediction and Decision Making among Patients with CirrhosisK08DK124577 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MAHMUD, NADIM · 2021 to 2025
$835k
Understanding Patient Preferences for Surgical Management in the Setting of Cirrhosis: A Mixed-Methods ApproachR03DK134794 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MAHMUD, NADIM · 2024 to 2025
$244k
Foundation for the National Institutes of Health K08-DK-124577-01A1NIDDK NIH HHS K08 DK124577NIDDK NIH HHS R03 DK134794
6 · The paper itself

Abstract

Patients with cirrhosis have increased surgical risk and require care team expertise. We explored the association between center cirrhosis surgical volume and postoperative mortality in a large VA data set. In this retrospective cohort study of 14,500 major surgeries in patients with cirrhosis, we found in adjusted analysis that high-volume centers (>16 surgeries in past year) had a 36% reduced hazard of postoperative mortality through 90 days vs low-volume centers (<9 surgeries in past year; hazard ratio 0.64, 95% confidence interval 0.43-0.94, P = 0.02). These findings demonstrate the importance of triaging patients with cirrhosis to high-volume centers for major surgery when feasible.

Indexed as

Hospitals, High-VolumeHospitals, Low-VolumeLiver CirrhosisPostoperative ComplicationsAgedFemaleHumansMaleMiddle AgedRetrospective StudiesUnited Statescirrhosisoperative optimizationpostoperative mortalitysurgical volume

Identifiers

PMID39835972
PMCPMC12277479

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.