ArticleJournal of virology2025
Generation of chimeric forms of rhesus macaque rhadinovirus expressing KSHV envelope glycoproteins gH and gL for utilization in an NHP model of infection.
Ryan D Estep, Helen Li, Aparna N Govindan, Kaidlyn A McDonald, Michael K Axthelm, Scott W Wong
Abstract read
In one paragraphArticle in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors.
Ryan D EstepVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA.ORCID 0000-0001-7785-8564 Helen LiVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA.
Aparna N GovindanVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA.
Kaidlyn A McDonaldVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA.
Michael K AxthelmVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA.
Scott W WongVaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA.ORCID 0000-0001-6855-0808 Funding
Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9MRHESUS HHV 8 HOMOLOGUE IN AIDS RELATED MALIGNANCIESR01CA075922 · NCI · OREGON REGIONAL PRIMATE RESEARCH CENTER · PI WONG, SCOTT W · 1997 to 2024
$16.7MInvestigating the development of AIDs and non-AIDS defining cancers in aged SIV-infected rhesus macaques.R01CA206404 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI WONG, SCOTT W · 2016 to 2020
$5.7MOral transmission of KSHV using rhesus macaque rhadinovirus modelR01CA275042 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SCOTT W WONG · 2022 to 2026
$4.0MTargeting CD180 to induce anti-KSHV response in nonhuman primatesU01CA295049 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SCOTT W WONG · 2024 to 2026
$3.5MArray Imaging digital PCR PlatformR44OD023028 · OD · COMBINATI, INC. · PI HUNG, PAUL JU-SUNG · 2018 to 2020
$1.8MIntegrated Digital PCR Platform with a Micromolded Siphoning ArrayR43OD023028 · OD · COMBINATI, INC. · PI HUNG, PAUL JU-SUNG · 2016 to 2017
$700kHHS | National Institutes of Health (NIH) R01-CA206404HHS | National Institutes of Health (NIH) R01-CA75922-24HHS | NIH | NIH Office of the Director (OD) P51-OD011092HHS | NIH | NIH Office of the Director (OD) U42-OD023028NCI NIH HHS R01 CA075922NCI NIH HHS R01 CA206404NCI NIH HHS R01 CA275042NCI NIH HHS U01 CA295049NIH HHS P51 OD011092NIH HHS R43 OD023028NIH HHS R44 OD023028
6 · The paper itselfAbstract
Kaposi's sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus associated with Kaposi's sarcoma and B cell malignancies. Like all herpesviruses, KSHV contains conserved envelope glycoproteins (gps) involved in virus binding, entry, assembly, and release from infected cells, which are also targets of the immune response. Due to the lack of a reproducible animal model of KSHV infection, the precise functions of the KSHV gps during infection
Indexed as
Herpesviridae InfectionsHerpesvirus 8, HumanRhadinovirusViral Envelope ProteinsAnimalsAntibodies, NeutralizingDisease Models, AnimalHumansMacaca mulattaVirus ReplicationAntibodies, NeutralizingViral Envelope Proteinschimeric virusglycoproteinsKaposi's sarcoma-associated herpesvirusrhesus rhadinovirusRRV BACvaccines
Identifiers
PMID39835812
PMCPMC11852781
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390