Evidence map›Paper›PMID 39835778›Full record

ArticleeLife2025

Mixed representations of choice direction and outcome by GABA/glutamate cotransmitting neurons in the entopeduncular nucleus.

Julianna Locantore, Yijun Liu, Jesse White, Janet Berrios Wallace, Celia Beron, Emily Kraft, Bernardo Sabatini, Michael Wallace

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Julianna LocantoreDepartment of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, United States.
Yijun LiuDepartment of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, United States.ORCID https://orcid.org/0009-0000-5612-7666
Jesse WhiteDepartment of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, United States.
Janet Berrios WallaceHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.
Celia BeronHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.ORCID https://orcid.org/0000-0003-4289-253X
Emily KraftDepartment of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, United States.
Bernardo SabatiniHoward Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, United States.ORCID https://orcid.org/0000-0003-0095-9177
Michael WallaceDepartment of Anatomy and Neurobiology, Boston University Chobanian & Avedisian School of Medicine, Boston, United States.ORCID https://orcid.org/0000-0002-7270-8521

Funding

Serotonergic modulation of the circuits and cell-types of the lateral habenulaR01MH133608 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Michael L Wallace · 2023 to 2026
$2.4M
Structure and function of the mouse parafasicular and entopeduncular nucleiR01NS103226 · NINDS · HARVARD MEDICAL SCHOOL · PI OSTEN, PAVEL, SABATINI, BERNARDO L · 2017 to 2021
$2.1M
A Function for the Entopeduncular Nucleus in Motivated BehaviorR00NS105883 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALLACE, MICHAEL L · 2021 to 2023
$744k
Graduate Training at the Interface of Neuroscience, Optical Engineering and Data ScienceT32NS136080 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI David A Boas, Jerry L Chen · 2024 to 2026
$661k
NIMH NIH HHS R01 MH133608NIMH NIH HHS R01MH133608NINDS NIH HHS R00 NS105883NINDS NIH HHS R00NS105883NINDS NIH HHS R01 NS103226NINDS NIH HHS R01NS103226NINDS NIH HHS T32 NS136080
6 · The paper itself

Abstract

The basal ganglia (BG) are an evolutionarily conserved and phylogenetically old set of sub-cortical nuclei that guide action selection, evaluation, and reinforcement. The entopeduncular nucleus (EP) is a major BG output nucleus that contains a population of GABA/glutamate cotransmitting neurons (EP

Indexed as

Choice BehaviorEntopeduncular Nucleusgamma-Aminobutyric AcidGlutamic AcidNeuronsAnimalsMaleSynaptic Transmissiongamma-Aminobutyric AcidGlutamic Acidbasal gangliacotransmissiondecision makingmouseneuroscience

Identifiers

PMID39835778
PMCPMC11750137

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.