Evidence map›Paper›PMID 39835775›Full record

ArticleeLife2025

Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma.

Odessa R Yabut, Jessica Arela, Hector G Gomez, Jesse Garcia Castillo, Thomas Ngo, Samuel J Pleasure

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Odessa R YabutDepartment of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, United States.
Jessica ArelaDepartment of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, United States.
Hector G GomezDepartment of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, United States.ORCID https://orcid.org/0000-0002-8894-0093
Jesse Garcia CastilloDepartment of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, United States.
Thomas NgoDepartment of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, United States.
Samuel J PleasureDepartment of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, United States.ORCID https://orcid.org/0000-0001-8599-1613

Funding

SDF1/CXCR4 Signaling and Tangential Neuronal Migration in the Developing CortexR01MH077694 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PLEASURE, SAMUEL JEREMY · 2007 to 2019
$5.0M
NeuroCovid Autoantibodies: Establishing a research pipelineR01NS118995 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PLEASURE, SAMUEL JEREMY · 2020 to 2024
$2.3M
The Role of Suppressor of Fused in Neural Stem Cells and its Implications in TumorigenesisK01CA201068 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YABUT, ODESSA · 2016 to 2019
$630k
American Brain Tumor Association A131363NCI NIH HHS K01 CA201068NIH HHS K01CA201068NIH HHS R01MH077694NIH HHS R01MH077694-S1NIH HHS R01NS118995NIH/NCI K01CA201068NIMH NIH HHS R01 MH077694NINDS NIH HHS R01 NS118995
6 · The paper itself

Abstract

Mutations in Sonic Hedgehog (SHH) signaling pathway genes, for example,

Indexed as

Cerebellar NeoplasmsFibroblast Growth FactorsHedgehog ProteinsMedulloblastomaNeural Stem CellsSignal TransductionAnimalsHumansMiceMice, KnockoutNeuronsRepressor ProteinsFibroblast Growth FactorsHedgehog ProteinsRepressor ProteinsShh protein, mouseSufu protein, mousedevelopmental biologyhumanmedulloblastomamouseneurosciencep53Sonic HedgehogSufu

Identifiers

PMID39835775
PMCPMC11750132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.