Evidence map›Paper›PMID 39835495›Full record

Trial reportJournal of hepato-biliary-pancreatic sciences2025

Capnographic monitoring using a novel mainstream system during endoscopic ultrasound and endoscopic retrograde cholangiopancreatography: A prospective randomized controlled trial.

Yoichi Takimoto, Eisuke Iwasaki, Masayasu Horibe, Seiichiro Fukuhara, Kazuhiro Minami, Shintaro Kawasaki, Tatsuhiro Masaoka, Haruhiko Ogata, Fateh Bazerbachi, Takanori Kanai

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of hepato-biliary-pancreatic sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yoichi TakimotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0001-8950-7809
Eisuke IwasakiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0001-8010-5117
Masayasu HoribeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Seiichiro FukuharaCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.
Kazuhiro MinamiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Shintaro KawasakiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Tatsuhiro MasaokaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Haruhiko OgataCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.
Fateh BazerbachiCentraCare, Interventional Endoscopy Program, St. Cloud Hospital, St. Cloud, Minnesota, USA.
Takanori KanaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeInsufficient studies exist on capnography efficacy during endoscopic ultrasound or endoscopic retrograde cholangiopancreatography, and no definitive conclusions have been drawn. To evaluate the feasibility and efficacy of a novel mainstream capnography using an over-the-biteblock end-tidal CO

methodsPatients undergoing EUS or ERCP with conscious sedation at a single Japanese center were randomized to a control or a novel capnography monitored (intervention) group in a 1:1 ratio. Hypoxemia correction maneuvers were pursued if the oxygen saturation decreased to <92% in the control or intervention group and if a 15-s suspension of EtCO

resultsIn total, 250 patients were enrolled without dropouts or missing data (control group: 125; capnography group: 125). There was no significant difference in the incidence of hypoxemia between the control and capnography groups (29.6% [37/125] vs. 26.4% [33/125]; p = .573). The estimated odds ratio was 0.925 (95% confidence interval: 0.708-1.208). The EtCO

conclusionsAlthough the novel mainstream capnography with an over-the-biteblock EtCO

Indexed as

CapnographyCholangiopancreatography, Endoscopic RetrogradeEndosonographyHypoxiaMonitoring, IntraoperativeAgedFeasibility StudiesFemaleHumansJapanMaleMiddle AgedMonitoring, PhysiologicProspective Studiescapnographyconscious sedationendoscopic retrograde cholangiopancreatographyendoscopic ultrasoundhypoxemia

Identifiers

PMID39835495
PMCPMC11926942

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.