Evidence map›Paper›PMID 39835471›Full record

ArticleJournal of cosmetic dermatology2025

Topographic Analysis of the Periorbital Region Including Orbicularis Oculi Muscle Based on Ultrasonography Interpretation.

Kyu-Lim Lee, Hee-Jin Kim

Erratum issuedAbstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kyu-Lim LeeDivision in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, South Korea.ORCID https://orcid.org/0000-0002-9898-2035
Hee-Jin KimDivision in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, South Korea.ORCID https://orcid.org/0000-0002-1139-6261

Funding

National Research Foundation of Korea RS-2023-00279373
6 · The paper itself

Abstract

objectiveUltrasonographic examination is easy, fast, safe, and used in various fields; however, its application to the facial area has been limited. Complex anatomical structures are mixed within thin, soft tissues in the facial region; therefore, understanding their structural characteristics is crucial. This study aimed to use ultrasonography to obtain information on the layered structure and soft tissue thickness of the eye area around the orbicularis oculi muscle and provide guidance for clinical practice.

methodsHealthy volunteers (33 men and 19 women; mean age: 28.4 years) underwent ultrasonography with nine reference points. The soft tissue thickness, including the orbicularis oculi muscle, was measured on monochromatic images. Ultrasonographic scans were performed at facial landmarks using linear transducers (IO8-17, E-CUBE15, Alpinion Medical System, Seoul, Korea), with images scanned transversely. The thickness was measured using ImageJ (National Institutes of Health, Bethesda, MD, USA).

resultsThe mean thickness of the orbicularis oculi muscle was 1.56 ± 0.45 mm (range 1.03-2.31 mm). The highest thickness was measured at the points VII (2.31 ± 0.68 mm) and VI (2.15 ± 0.48 mm). The mean depth of the orbicularis oculi muscle was 1.63 ± 0.62 mm (range 0.88-2.80 mm), and the most superficial point was 0.88 ± 0.99, at point VII.

conclusionThis study provides critical anatomical data that can enhance the precision of ultrasound-guided procedures in the periorbital area, allowing clinicians to accurately target the muscle layer and soft tissue structures. By utilizing these findings, practitioners can optimize treatment effectiveness, reduce complications, and improve outcomes in cosmetic procedures such as botulinum toxin injections, filler placements, and other non-invasive facial treatments. The detailed anatomical insights gained from this study will help bridge the gap between anatomical understanding and clinical application, promoting safer and more efficient aesthetic interventions.

Indexed as

Facial MusclesAdultAnatomic LandmarksEyelidsFemaleHealthy VolunteersHumansMaleOrbitUltrasonographyYoung Adultorbicularis oculi muscleperiorbital regionsoft tissue thicknessultrasonography

Identifiers

PMID39835471
PMCPMC11748098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.