Evidence map›Paper›PMID 39835154›Full record

SynthesisFrontiers in neurology2024

Robot-assisted upper limb therapy for personalized rehabilitation in children with cerebral palsy: a systematic review.

Daniela Cardone, David Perpetuini, Marta Di Nicola, Arcangelo Merla, Giovanni Morone, Irene Ciancarelli, Antimo Moretti, Francesca Gimigliano, Alice Cichelli, Francesco De Flaviis and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniela CardoneDepartment of Engineering and Geology, University "G. d'Annunzio" of Chieti-Pescara, Pescara, Italy.
David PerpetuiniDepartment of Engineering and Geology, University "G. d'Annunzio" of Chieti-Pescara, Pescara, Italy.
Marta Di NicolaDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.
Arcangelo MerlaDepartment of Engineering and Geology, University "G. d'Annunzio" of Chieti-Pescara, Pescara, Italy.
Giovanni MoroneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Irene CiancarelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Antimo MorettiDepartment of Medical and Surgical Specialties and Dentistry, University of Campania Luigi Vanvitelli, Napels, Italy.
Francesca GimiglianoDepartment of Medical and Surgical Specialties and Dentistry, University of Campania Luigi Vanvitelli, Napels, Italy.
Alice CichelliDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.
Francesco De FlaviisDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.
Alex Martino CinneraDepartment of Medical and Surgical Specialties and Dentistry, University of Campania Luigi Vanvitelli, Napels, Italy.
Teresa PaolucciDepartment of Oral Medical Science and Biotechnology, Physical and Rehabilitation Medicine, BIND, CARES, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cerebral palsy (CP) is a group of permanent disorders of movement development that may cause activity limitations. In this context, robot-assisted therapy might play a key role in clinical management. This comprehensive systematic review aimed to investigate the efficacy of robotic systems in improving upper limb (UL) functions in children with CP. Methods: PubMed, EMBASE, Scopus, and PEDro were searched from inception to February 2024. The risk of bias was assessed with the Joanna Briggs Institute critical appraisal tools battery. Results: Of 756 articles identified, 14 studies involving 193 children with CP with a judged to be of good methodological quality, but with a lack in the study design, were included in the final synthesis. In the included studies a wide range of devices was used, both exoskeletons and end-effectors, both wearable and non-wearable. The CP children who underwent robot-assisted therapy reported a significant overall increase in clinical assessment, specifically in UL movements and manual dexterity. The clinical improvement was often accompanied by a gain also in instrumental assessments (i.e., kinematic analysis, EMG). Discussion: The present review suggested that robot-assisted therapy can improve UL motor functions in children with CP. Moreover, the availability of different devices with adjustable parameters can represent an important resource in proposing patient-centered-personalized rehabilitation protocols to enhance the efficacy of rehabilitation and integration into daily life. However, the limited sample size and lack of standardized and clearly reproducible protocols impose to recommend the use of robot-assisted therapy as an integration to usual rehabilitation and not as a replacement. Systematic review registration: https://osf.io/a78zb/.

Indexed as

endeffectorexoskeletonhemiplegiarehabilitationroboticsupper extremities

Identifiers

PMID39835154
PMCPMC11743387

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.