ReviewCureus2024
Anatomic and Functional Outcomes of Scleral Buckling Surgery for Advanced Retinopathy of Prematurity: A Systematic Review and Proportional Meta-Analysis.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A significant percentage of patients with retinopathy of prematurity (ROP) who progressed to stages 4 and 5 of ROP will require surgical intervention. Scleral buckling surgery is widely employed for the restoration of retinal detachment in advanced cases of ROP. This systematic review and meta-analysis aim to review the anatomical and visual outcomes following scleral buckling surgery in ROP of stages 4 and 5. We performed a systematic literature search in two databases (MEDLINE and EMBASE), according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines, from January 2000 to July 2024 for studies examining the anatomical and functional outcomes resulting from the scleral buckling procedure in premature infants with advanced ROP. We used the inverse variance random effects model to calculate pooled effect estimates and conducted a single-arm proportional meta-analysis. The study was conducted based on a prespecified protocol registered in the International Prospective Register of Systematic Reviews (PROSPERO) database with registration number CRD42024557314. Ten eligible studies for our systematic review were identified. The pooled prevalence for the anatomic outcome, that is the proportion of retinal reattachment, was estimated at 65% (95% Cl [0.49 - 0.82], p-value 0 < 0.0001). The visual outcome was investigated through five studies. The prevalence of normal visual acuity or mild visual impairment, defined as visual acuity between 6/18 and 6/60 as per the World Health Organisation (WHO) visual impairment recommendations, was calculated at 41% (95% Cl [0.29; 0.52], p-value < 0.0001, I
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