ArticleCureus2024
An Unexpected Case of Clear Cell Adenocarcinoma of the Cervix in a Non-Diethylstilbestrol-Exposed Postmenopausal Woman.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Clear cell adenocarcinoma of the cervix (CCAC) is a rare subtype of cervical adenocarcinoma. It has been linked to intrauterine exposure to diethylstilbestrol (DES) but can happen in non-DES-exposed patients, albeit less commonly. Presentation is largely vaginal bleeding, emphasizing the importance of considering CCAC in the differential of abnormal vaginal bleeding despite the tumor's rarity. We present the case of a non-DES-exposed 68-year-old woman who presented with postmenopausal bleeding (PMB). The patient underwent total abdominal hysterectomy after misdiagnosis as clear cell endometrial adenocarcinoma, later diagnosed as CCAC. We encourage consideration of clear cell adenocarcinoma of the cervix in the differential diagnosis of PMB even in patients without DES exposure and for physicians to advocate for patients to keep up to date with cervical cancer screenings.
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