ReviewCureus2024
Efficacy and Safety of Tranexamic Acid in the Management of Gastrointestinal Bleeding: A Systematic Review.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The efficacy and safety of tranexamic acid use during radical cystectomy A systematic review and meta-analysis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lower gastrointestinal bleeding (LGIB) is a challenging and potentially life-threatening medical condition that often necessitates prompt intervention. In the quest to improve patient outcomes, one therapeutic agent has garnered significant attention - tranexamic acid (TXA). The basic aim of the study is to systematically review the role of TXA in LGIB. This systematic review adheres to the guidelines outlined in The Checklist for critical Appraisal and data extraction for systematic Reviews of prediction Modelling Studies, known as the CHARMS checklist, to ensure the rigorous and reproducible evaluation of predictive models. The study extends beyond the initial protocol to include a report on calibration, in addition to the originally planned assessments of discrimination, validation, and model quality. The findings revealed diverse effect sizes and precision in TXA's impact on LGIB outcomes across the studies. While some studies reported substantial effects, others exhibited more modest results, emphasizing the complexity of LGIB management. Risk of bias assessments unveiled variations in methodological quality, urging caution in interpretation. It is concluded that the role of TXA in LGIB is complex, with diverse findings and methodological considerations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.