ArticleCureus2024
Acute Kidney Injury Due to Ureteral Damage by Needle-Shaped Crystals Associated With Boron Neutron Capture Therapy.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A LAT1-selective PET tracer, 5-[¹⁸F]F-αMe-3BPA, as a companion to its structurally matched ¹⁰B analog in boron neutron capture therapy.European journal of nuclear medicine and molecular imaging · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 77-year-old man was referred to our department because of macrohematuria, oliguria, and a serum creatinine level of 2.47 mg/dL during boron neutron capture therapy (BNCT) for oropharyngeal cancer. At baseline, his creatinine level had been 0.98 mg/dL. The vital signs and physical examination were normal. A urinalysis showed protein and numerous red cells per high-power field, and needle-shaped crystals were observed. A plane computed tomography showed hematoma within the extensive ureter. However, hydronephrosis was not recognized. Immediate discontinuation of BNCT and supplemental fluids reduced gross hematuria, increased urine, and creatinine decreased to 0.97 mg/dL. BNCT is an innovative radiation therapy that targets tumor cells by inducing a nuclear reaction between 10B and neutrons within the tumor. However, there have been no reported cases of treatment-related boron crystals causing ureteral injury that leads to acute kidney injury, and oncologists should be aware of this potential risk.
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Registered trials
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