Evidence map›Paper›PMID 39834863›Full record

ArticleiScience2025

Connectional differences between humans and macaques in the MT+ complex.

Jianxiong Ruan, Ye Yuan, Yicheng Qiao, Minghao Qiu, Xueda Dong, Yue Cui, Jianhong Wang, Ning Liu

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Single-Trial fMRI Decoding of 3D Motion with Stereoscopic and Perspective Cues.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianxiong RuanSchool of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230026, China.
Ye YuanState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yicheng QiaoState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Minghao QiuNational Resource Center for Non-Human Primates and National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Xueda DongState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yue CuiLaboratory of Brain Atlas and Brain-inspired Intelligence, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
Jianhong WangNational Resource Center for Non-Human Primates and National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Ning LiuState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MT+ is pivotal in the dorsal visual stream, encoding tool-use characteristics such as motion speed and direction. Despite its conservation between humans and monkeys, differences in MT+ spatial location and organization may lead to divergent, yet unexplored, connectivity patterns and functional characteristics. Using diffusion tensor imaging, we examined the structural connectivity of MT+ subregions in macaques and humans. We also employed graph-theoretical analyses on the constructed homologous tool-use network to assess their functional roles. Our results revealed location-dependent connectivity in macaques, with MST, MT, and FST predominantly connected to dorsal, middle, and ventral surfaces, respectively. Humans showed similar connectivity across all subregions. Differences in connectivity between MST and FST are more pronounced in macaques. In humans, the entire MT+ region, especially MST, exhibited stronger information transmission capabilities. Our findings suggest that the differences in tool use between humans and macaques may originate earlier than previously thought, particularly within the MT+ region.

Indexed as

Biological sciencesComputer sciencePhysics

Identifiers

PMID39834863
PMCPMC11743884

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.