Evidence map›Paper›PMID 39834716›Full record

ArticleEClinicalMedicine2025

Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort study.

Safoora Gharibzadeh, Ash Routen, Cameron Razieh, Francesco Zaccardi, Claire Lawson, Clare Gillies, Simon Heller, Melanie Davies, Helen Atkins, Stephen C Bain and 38 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Safoora GharibzadehLeicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
Ash RoutenDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK.
Cameron RaziehLeicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
Francesco ZaccardiLeicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
Claire LawsonLeicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
Clare GilliesLeicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
Simon HellerDepartment of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Melanie DaviesNational Institute for Health Research (NIHR) Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and the University of Leicester, Leicester, UK.
Helen AtkinsUniversity Hospitals of Leicester NHS Trust, Leicester, UK.
Stephen C BainSwansea University Medical School, Swansea, UK.
Nazir L LoneCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.
Krisnah PoinasamyAsthma and Lung UK, London, UK.
Tunde PetoDepartment of Clinical Ophthalmology, Institute of Ophthalmology, University College London, London University, London, UK.
Elizabeth RobertsonDiabetes UK, London, UK.
Bob YoungDiabetes UK, London, UK.
Desmond JohnstonFaculty of Medicine, Imperial College London, London, UK.
Jennifer QuintNHLI, Imperial College London, London, UK.
Jonathan ValabhjiDivision of Metabolism, Digestion & Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Khalida IsmailDepartment of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
Michael MarksHospital for Tropical Diseases, University College London Hospital, London, UK.
Alex HorsleyManchester University NHS Foundation Trust, Manchester, UK.
Annemarie DochertyCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.
Ewen HarrisonCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.
James ChalmersMRC Human Immunology Unit, University of Oxford, Oxford, UK.
Ling-Pei HoRadcliffe Department of Medicine, University of Oxford, Oxford, UK.
Betty RamanOxford University Hospitals NHS Foundation Trust, Oxford, UK.
Chris BrightlingCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Omer ElneimaCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Rachel EvansUniversity Hospitals of Leicester NHS Trust, Leicester, UK.
Neil GreeningCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Victoria C HarrisUniversity Hospitals of Leicester NHS Trust, Leicester, UK.
Linzy Houchen-WolloffNIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Marco SerenoNIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Aarti ShikotraDepartment of Population Health Sciences, University of Leicester, Leicester, UK.
Amisha SingapuriCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Louise WainMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Claudia LangenbergPrecision Healthcare University Research Institute - PHURI, Queen Mary University London; And Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.
John DennisSchool of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Northern Ireland, UK.
John PetrieSchool of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Clarice Pears Building, Level 5 90 Byres Road, Glasgow, G12 8TB, UK.
Naveed SattarDivision of Metabolism, Digestion & Reproduction, Faculty of Medicine, Imperial College London, London, UK.
Olivia LeavyMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Mattew RichardsonCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Ruth M SaundersCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Anne McArdleDepartment of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool and MRC- Arthritis Research UK Centre for Integrated Research Into Musculoskeletal Ageing (CIMA), UK.
Hamish McASuleyCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Tom YatesDiabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK.
Kamlesh KhuntiLeicester Real World Evidence Unit, Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
PHOSP-COVID Study Collaborative Group

Funding

British Heart Foundation CH/F/21/90010
6 · The paper itself

Abstract

Background: People with diabetes are at increased risk of hospitalisation, morbidity, and mortality following SARS-CoV-2 infection. Long-term outcomes for people with diabetes previously hospitalised with COVID-19 are, however, unknown. This study aimed to determine the longer-term physical and mental health effects of COVID-19 in people with and without diabetes. Methods: The PHOSP-COVID study is a multicentre, long-term follow-up study of adults discharged from hospital between 1 February 2020 and 31 March 2021 in the UK following COVID-19, involving detailed assessment at 5 and 12 months after discharge. The association between diabetes status and outcomes were explored using multivariable linear and logistic regressions. Findings: People with diabetes who survived hospital admission with COVID-19 display worse physical outcomes compared to those without diabetes at 5- and 12-month follow-up. People with diabetes displayed higher fatigue (only at 5 months), frailty, lower physical performance, and health-related quality of life and poorer cognitive function. Differences in outcomes between diabetes status groups were largely consistent from 5 to 12-months. In regression models, differences at 5 and 12 months were attenuated after adjustment for BMI and presence of other long-term conditions. Interpretation: People with diabetes reported worse physical outcomes up to 12 months after hospital discharge with COVID-19 compared to those without diabetes. These data support the need to reduce inequalities in long-term physical and mental health effects of SARS-CoV-2 infection in people with diabetes. Funding: UK Research and Innovation and National Institute for Health Research. The study was approved by the Leeds West Research Ethics Committee (20/YH/0225) and is registered on the ISRCTN Registry (ISRCTN10980107).

Indexed as

Covid-19DiabetesLong Covid

Identifiers

PMID39834716
PMCPMC11743801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.