ArticleEngineering in life sciences2025
Synthesis and Evaluation of PCL/Chitosan/CQD-Fe Magnetic Nanocomposite for Wound Healing: Emphasis on Gene Expression.
Article in Engineering in life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Carbon-based quantum dots enhance platelets aggregation through migrasomes biogenesis.Journal of nanobiotechnology · 2026Article
Corrections and comments
- Retraction · 2025-08-13Compromised Peer Review · Investigation by Journal/Publisher ·
- Retracted
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of an effective and rapid method for healing the skin is of crucial importance. In this study, we prepared a porous scaffold made of polycaprolactone (PCL) and carbon quantum dots (CQDs), Fe, and Chitosan (Cs) as the scaffold core to cover the skin. Then evaluated antibacterial, biocompatibility, and wound healing properties as well as the expression of genes effective in wound healing. The PCL/Cs/CQD-Fe scaffold was synthesized via electrospinning and was evaluated of morphology, functional groups, and structure through Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), and x-ray diffraction (XRD). The viability of the L929 fibroblast stem cells was obtained. The antibacterial effect, biocompatibility, and wound healing efficiency of the scaffold were investigated through minimum inhibitory concentration (MIC), (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), and tissue analysis. The relative expression of genes platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-β), and matrix metalloproteinase-1 (MMP1) was assessed through RT-PCR. The results of SEM showed the successful integration of the PCL scaffold with CQD-Fe and Cs. The mean size of PCL/Cs/CQD-Fe nanocomposite was in the range of 0.135-32.6 nm. The results of FTIR showed the formation of a link between CQD nanoparticles and Fe. The vibrating-sample magnetometer (VSM) proved the super para magnetism of the CQD-Fe magnetic nanoparticles (0.38 emu/g). The MIC of Cs/CQD-Fe against
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Registered trials
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