Evidence map›Paper›PMID 39834365›Full record

ArticleFrontiers in microbiology2024

High prevalence of fecal carriage of extended-spectrum beta-lactamase producing

Magreth Erick Macha, Weihong Qi, Salome N Seiffert, Anja Bösch, Philipp Kohler, Honorathy Msami Urassa, Sabine Haller, Erin West, Maja Weisser Rohacek, Baharak Babouee Flury

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Magreth Erick MachaSt. Francis University College of Health and Allied Sciences, Ifakara, Tanzania.
Weihong QiFunctional Genomics Center Zurich, University of Zürich/ETH Zürich, Zürich, Switzerland.
Salome N SeiffertDivision of Human Microbiology, Centre for Laboratory Medicine, St. Gallen, Switzerland.
Anja BöschMedical Research Center, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Philipp KohlerDivision of Infectious Diseases, Infection Prevention, and Travel Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Honorathy Msami UrassaSt. Francis Regional Referral Hospital, Ifakara, Tanzania.
Sabine HallerDivision of Infectious Diseases, Infection Prevention, and Travel Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Erin WestClinical Trials Unit, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Maja Weisser RohacekDivision of Infectious Diseases, University Hospital Basel, Basel, Switzerland.
Baharak Babouee FluryMedical Research Center, Kantonsspital St. Gallen, St. Gallen, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The global rise of extended-spectrum beta-lactamase-producing Methods: This cross-sectional study was conducted at St. Francis Regional Referral Hospital, Ifakara, Tanzania, from October 2021 to August 2023, involving 326 UTI patients. Demographic data and resistance risk factors were collected via structured questionnaires. Stool samples collected pre-antibiotic treatment were screened for ESBL-PE and carbapenemase locally. Positive samples underwent further analysis in Switzerland using MALDI-ToF, Vitek MS, and whole-genome sequencing. Multivariable analysis assessed predictors associated with ESBL-PE carriage for risk factors with Results: We enrolled 326 UTI patients (median age: 35.5 years, range: 25-52) and 189 (58.0%) were females. Fecal ESBL-PE colonization was detected in 70.9% of patients, predominantly Conclusion: The high prevalence of ESBL-PE fecal carriage in rural Tanzania highlights the need for improved infection control and further research into community transmission dynamics.

Indexed as

enterobacteralesextended-spectrum beta-lactamasefecal carriagerural Tanzaniaurinary tract infections

Identifiers

PMID39834365
PMCPMC11743186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.