Evidence map›Paper›PMID 39834265›Full record

ArticleEuropean journal of translational myology2025

Oxy-inflammation in hyperbaric oxygen therapy applications.

Gerardo Bosco, Andrea Brizzolari, Matteo Paganini, Enrico Camporesi, Alessandra Vezzoli, Simona Mrakic-Sposta

Abstract read
In one paragraph

Article in European journal of translational myology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gerardo BoscoDepartment of Biomedical Sciences, University of Padua, Padua. gerardo.bosco@unipd.it.
Andrea BrizzolariDepartment of Biomedical Sciences, University of Padua, Padua. andrea.brizzolari@unipd.it.
Matteo PaganiniDepartment of Biomedical Sciences, University of Padua, Padua. matteo.paganini@unipd.it.
Enrico CamporesiTEAM Health Anaesthesia, Tampa General Hospital, Tampa, Florida. ecampore@usf.edu.
Alessandra VezzoliInstitute of Clinical Physiology, National Research Council (IFC-CNR), Milan. alessandra.vezzoli@cnr.it.
Simona Mrakic-SpostaInstitute of Clinical Physiology, National Research Council (IFC-CNR), Milan. simona.mrakicsposta@cnr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperbaric Oxygen Therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined protocols and is monitored by trained personnel. HBOT relies on increasing the inspired O2 fraction (fiO2) and elevating the partial pressure of O2 (pO2). O2 is typically administered at pressures between 1.5 and 3.0 ATA for 60 to 120 minutes, depending on the clinical presentation. Currently, there are 15 indications for HBOT approved by the Undersea and Hyperbaric Medicine Society, categorized into three groups: emergency medicine, wound healing acceleration, and antimicrobial effects. The present narrative review aims to elucidate the mechanisms action underlying HBOT, particularly oxy-inflammation, in various pathologies within these categories.

Identifiers

PMID39834265
PMCPMC12038570

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.