Evidence map›Paper›PMID 39834223›Full record

ArticleJournal of Korean medical science2025

Prognostic Value of Ambulatory Status at Transplant in Older Heart Transplant Recipients: Implications for Organ Allocation Policy.

Junho Hyun, Jong-Chan Youn, Jung Ae Hong, Darae Kim, Jae-Joong Kim, Myoung Soo Kim, Jaewon Oh, Jin-Jin Kim, Mi-Hyang Jung, In-Cheol Kim and 11 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Junho HyunDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4211-3081
Jong-Chan YounDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Korea. jong.chan.youn@gmail.com.ORCID https://orcid.org/0000-0003-0998-503X
Jung Ae HongDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3991-7353
Darae KimDivision of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3284-0904
Jae-Joong KimDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2714-2282
Myoung Soo KimDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8975-8381
Jaewon OhDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University of College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4585-1488
Jin-Jin KimDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-9054-2249
Mi-Hyang JungDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-0224-5178
In-Cheol KimDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-5751-2328
Sang-Eun LeeDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7290-2463
Jin Joo ParkCardiovascular Center, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0001-9611-1490
Min-Seok KimDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0860-3650
Sung-Ho JungDepartment of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3699-0312
Hyun-Jai ChoDivision of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-2779-4037
Hae-Young LeeDivision of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-9521-4102
Seok-Min KangDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University of College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9856-9227
Dong-Ju ChoiCardiovascular Center, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0003-0146-2189
Jon A KobashigawaDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0001-9308-3172
Josef StehlikDivision of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID https://orcid.org/0000-0002-7362-0513
Jin-Oh ChoiDivision of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. choijean5@gmail.com.ORCID https://orcid.org/0000-0002-2441-2267

Funding

Catholic Medical CenterKorea National Institute of Health 2014-ER6301-00Korea National Institute of Health 2014-ER6301-01Korea National Institute of Health 2014-ER6301-02Korea National Institute of Health 2017-ER6301-00Korea National Institute of Health 2017-ER6301-01Korea National Institute of Health 2017-ER6301-02Korea National Institute of Health 2020-ER7201-00Korea National Institute of Health 2023-ER0805-00Korea National Institute of Health 2023-ER0805-01National Research Foundation of Korea NRF-2021R1F1A1063430
6 · The paper itself

Abstract

backgroundShortage of organ donors in the Republic of Korea has become a major problem. To address this, it has been questioned whether heart transplant (HTx) allocation should be modified to reduce priority of older patients. We aimed to evaluate post-HTx outcomes according to recipient age and specific pre-HTx conditions using a nationwide prospective cohort.

methodsWe analyzed clinical characteristics of 628 patients from the Korean Organ Transplant Registry who received HTx from January 2015 to December 2020. Enrolled recipients were divided into three groups according to age. We also included comorbidities including ambulatory status. Non-ambulatory status was defined as pre-HTx support with either extracorporeal membrane oxygenation, continuous renal replacement therapy, or mechanical ventilation.

resultsOf the 628 patients, 195 were < 50 years, 322 were 50-64 years and 111 were ≥ 65 years at transplant. Four hundred nine (65.1%) were ambulatory and 219 (34.9%) were non-ambulatory. Older recipients tended to have more comorbidities, ischemic cardiomyopathy, and received older donors. Post-HTx survival was significantly lower in older recipients (

conclusionOur results do not support use of age alone as an allocation criterion. Transplant candidate age in combination with some comorbidities such as non-ambulatory status may identify patients at a sufficiently elevated risk at which suitability of HTx should be reconsidered.

Indexed as

Heart TransplantationAdultAgedAge FactorsComorbidityFemaleHumansMaleMiddle AgedPrognosisProspective StudiesRegistriesRepublic of KoreaTissue and Organ ProcurementTransplant RecipientsAgeAmbulatory StatusHeart TransplantationOutcomeSurvival

Identifiers

PMID39834223
PMCPMC11745924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.