Evidence map›Paper›PMID 39834104›Full record

ArticleMagnetic resonance in medicine2025

Learning-based motion artifact correction in the Z-spectral domain for chemical exchange saturation transfer MRI.

Munendra Singh, Sultan Z Mahmud, Vivek Yedavalli, Jinyuan Zhou, David Olayinka Kamson, Peter van Zijl, Hye-Young Heo

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Munendra SinghDepartment of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.
Sultan Z MahmudDepartment of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.
Vivek YedavalliDepartment of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.
Jinyuan ZhouDepartment of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-6684-7920
David Olayinka KamsonDepartment of Oncology, Johns Hopkins University, Baltimore, Maryland, USA.
Peter van ZijlDepartment of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.
Hye-Young HeoDepartment of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-7297-2015

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
Development and Translation of D-glucose as a Diagnostic Agent for MRI of CancerR01EB034978 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Linda Knutsson, Peter CM Van Zijl · 2023 to 2026
$2.5M
Ultrafast Quantitative pH MRI for Acute Ischemic Stroke PatientsR01NS112242 · NINDS · JOHNS HOPKINS UNIVERSITY · PI HEO, HYE YOUNG · 2020 to 2024
$1.9M
Chemical Exchange Saturation Transfer MR FingerprintingR01EB029974 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI HEO, HYE YOUNG · 2021 to 2024
$1.4M
NIBIB NIH HHS P41 EB031771NIBIB NIH HHS R01 EB029974NIBIB NIH HHS R01 EB034978NICHD NIH HHS P50 HD103538NIH HHS P41EB031771NIH HHS R01EB029974NIH HHS R01EB034978NIH HHS R01NS112242NINDS NIH HHS R01 NS112242
6 · The paper itself

Abstract

purposeTo develop and evaluate a physics-driven, saturation contrast-aware, deep-learning-based framework for motion artifact correction in CEST MRI.

methodsA neural network was designed to correct motion artifacts directly from a Z-spectrum frequency (Ω) domain rather than an image spatial domain. Motion artifacts were simulated by modeling 3D rigid-body motion and readout-related motion during k-space sampling. A saturation-contrast-specific loss function was added to preserve amide proton transfer (APT) contrast, as well as enforce image alignment between motion-corrected and ground-truth images. The proposed neural network was evaluated on simulation data and demonstrated in healthy volunteers and brain tumor patients.

resultsThe experimental results showed the effectiveness of motion artifact correction in the Z-spectrum frequency domain (MOCO

conclusionThe MOCO

Indexed as

ArtifactsDeep LearningImage Processing, Computer-AssistedMagnetic Resonance ImagingAdultAlgorithmsBrainBrain NeoplasmsComputer SimulationHumansMotionMovementNeural Networks, ComputerPhantoms, ImagingAPTCESTdeep‐learningmotion artifact correction

Identifiers

PMID39834104
PMCPMC12021334

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.