Evidence map›Paper›PMID 39834093›Full record

ArticleMagnetic resonance in medicine2025

Generalizable, sequence-invariant deep learning image reconstruction for subspace-constrained quantitative MRI.

Zheyuan Hu, Zihao Chen, Tianle Cao, Hsu-Lei Lee, Yibin Xie, Debiao Li, Anthony G Christodoulou

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zheyuan HuDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0002-0276-8254
Zihao ChenDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0001-7838-4989
Tianle CaoDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0003-3739-3103
Hsu-Lei LeeBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Yibin XieBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Debiao LiDepartment of Bioengineering, University of California, Los Angeles, California, USA.
Anthony G ChristodoulouDepartment of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0002-9334-8684

Funding

Expanding on a new paradigm for MRI in pediatric congenital heart diseaseR01HL127153 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHRISTODOULOU, ANTHONY G, FINN, JOHN PAUL · 2015 to 2024
$6.1M
Motion-Resolved, Comprehensive Quantitative Tissue Characterization Using MR MultitaskingR01EB028146 · NIBIB · CEDARS-SINAI MEDICAL CENTER · PI CHRISTODOULOU, ANTHONY G, LI, DEBIAO · 2019 to 2022
$2.5M
SSFP Cardiovascular MR Imaging on 3.0T Using Unified-Coil Local ShimmingR01HL156818 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SPINCEMAILLE, PASCAL, YANG, HSIN-JUNG · 2021 to 2024
$2.5M
NHLBI NIH HHS R01 HL127153NHLBI NIH HHS R01 HL156818NIBIB NIH HHS R01 EB028146NIH HHS NIH R01EB028146NIH HHS NIH R01HL127153NIH HHS NIH R01HL156818
6 · The paper itself

Abstract

purposeTo develop a deep subspace learning network that can function across different pulse sequences.

methodsA contrast-invariant component-by-component (CBC) network structure was developed and compared against previously reported spatiotemporal multicomponent (MC) structure for reconstructing MR Multitasking images. A total of 130, 167, and 16 subjects were imaged using T

resultsThe proposed CBC showed significantly better normalized root mean squared error than MC in both matched-sequence and unmatched-sequence experiments (p < 0.001), fewer structural details in quantitative error maps, and tighter limits of agreement. CBC was more generalizable than MC (smaller performance loss; p = 0.006 in T

conclusionContrast-invariant learning of spatial features rather than spatiotemporal features improves performance and generalizability, addresses data scarcity, and offers a pathway to universal supervised deep subspace learning.

Indexed as

Deep LearningImage Processing, Computer-AssistedMagnetic Resonance ImagingAdultAlgorithmsFemaleHumansImage Interpretation, Computer-AssistedMaleReproducibility of Resultscardiac MRIdeep learningdeep subspace learningMR Multitaskingmulti‐parametric mappingsubspace‐constrained quantitative MRI

Identifiers

PMID39834093
PMCPMC12021335

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.