Evidence map›Paper›PMID 39834082›Full record

ArticleMagnetic resonance in medicine2025

CESTsimu: An open-source GUI for spectral and spatial CEST simulation.

Huabin Zhang, Bensheng Qiu, Jiadi Xu, Kannie Wy Chan, Jianpan Huang

Abstract read
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In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huabin ZhangDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-5170-2753
Bensheng QiuDepartment of Electronic Engineering and Information Science, University of Science and Technology of China, Hefei, China.ORCID https://orcid.org/0000-0003-2987-7378
Jiadi XuRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0001-9698-5622
Kannie Wy ChanRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-7315-1550
Jianpan HuangDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0002-4453-8764

Funding

Health and Medical Research Fund 21222621Li Ka Shing Faculty of Medicine, The University of Hong Kong 204610401Li Ka Shing Faculty of Medicine, The University of Hong Kong 204610519National Natural Science Foundation of China 82402225The University of Hong Kong 109000487The University of Hong Kong 109001694The University of Hong Kong 200000341
6 · The paper itself

Abstract

purposeThe aim of this study was to create a user-friendly CEST simulation tool with a GUI for both spectral (1D Z-spectra) and spatial (2D phantom) CEST experiments, making the CEST simulation easier to perform.

methodsCESTsimu was developed using MATLAB App Designer. It consists of three modules: Saturation Settings, Exchange Settings, and Phantom Settings. CESTsimu can not only import/export files in the defined format but can also import files generated by other existing simulation platforms (e.g. pulseq-CEST).

resultsThe 1D Z-spectrum simulation results demonstrated the effectiveness of CESTsimu in simulating Z-spectra under various saturation (

conclusionWe developed a user-friendly CESTsimu GUI for intuitively simulating CEST experiments under diverse saturation and exchange settings in 1D and 2D conditions. CESTsimu has the potential to facilitate the broad utilization of CEST MRI among a wide range of users.

Indexed as

Image Processing, Computer-AssistedMagnetic Resonance ImagingSoftwareAlgorithmsBrainComputer SimulationHumansPhantoms, Imaging1D Z‐spectra2D phantomBloch‐McConnell equationCEST simulationgraphical user interface

Identifiers

PMID39834082
PMCPMC11971506

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.