ReviewJournal of cardiothoracic surgery2025
Accuracy of Freestyle Libre continuous glucose monitoring system in critically ill patients after cardiac surgery.
Review in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Perioperative use and accuracy of continuous glucose monitoring: A systematic review.Diabetes, obesity & metabolism · 2025Pooled it
- Subcutaneous glucose tracking during extreme perioperative perfusion stress: a prospective microdialysis study.Journal of clinical monitoring and computing · 2026Article
- Relationship between stress hyperglycemia ratio and gastrointestinal bleeding and mortality after coronary artery bypass grafting: a multicenter cohort study.Frontiers in cardiovascular medicine · 2026Article
- Accuracy and Clinical Safety of the FreeStyle Libre 2 System in an Internal Medicine Intermediate Care Unit.Cureus · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundHyperglycemia is an independent risk factor for perioperative complications and mortality after cardiac surgery. Freestyle Libre Continuous glucose monitor (CGM) is an interstitial glucose monitoring system, which has been proven to be stable and accurate in various disease. MATERIALS AND
methods86 patients with hyperglycemia after cardiac surgery between October 2021 and October 2022 in the cardiovascular ICU, were enrolled in this study. We evaluated systematic errors and numerical accuracy in blood glucose (BG) between two groups using Bland-Altman analysis and mean absolute relative difference (MARD). The clinical accuracy was assessed by consensus and Clarke error grid.
results435 paired sensor-reference values were enrolled between the Freestyle and venous BG. The MARD was 18.2% with the Bland-Altman standard bias of 31.87 mg/dL. 1851 paired values were enrolled between the Freestyle and arterial BG. The MARD was 21.5%, and the Bland-Altman standard bias was 41.45 mg/dL. 432 paired values were enrolled between the arterial and venous BG. The MARD was 8.4%, and the Bland-Altman standard bias was - 9.95 mg/dL.
conclusionsOur study demonstrated the relatively low accuracy of Freestyle Libre CGM for critical patients after cardiac surgery. The arterial blood gas glucose analysis acts as an effective tool to improve BG management.
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Registered trials
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