Evidence map›Paper›PMID 39833916›Full record

ArticleArchives of public health = Archives belges de sante publique2025

Underestimated latent tuberculosis infection burden among school contacts in China: a cross-sectional study.

Jin Yin, Mei Wang, Chengguo Wu, Yaling Shi, Ying Liu, Ya Yu, Qian Su, Zhengyu Zhang, Xueyong Huang, Xiaoshuang Zhang and 2 more

Abstract read
In one paragraph

Article in Archives of public health = Archives belges de sante publique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jin Yin *Chongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Mei Wang *Chongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Chengguo WuChongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Yaling ShiChongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Ying LiuChongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Ya YuChongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Qian SuChongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Zhengyu ZhangChongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Xueyong HuangChongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Xiaoshuang ZhangChongqing Beibei District Center for Disease Control and Prevention, Chongqing, 400700, China.
Jun Fan *Chongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Bo Wu *Chongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China. 957571316@qq.com.

Funding

Chongqing Health Commission Medical Science Research Project 2024WSJK08Chongqing Municipal Institute of Tuberculosis Research Project 2022CQJFS04Chongqing Science and Health Joint Research Project 2023MSXM143Chongqing Science and Health Joint Research Project 2023ZDXM027
6 · The paper itself

Abstract

backgroundPrevious research has indicated a low tuberculin skin tests (TST) strong positive rate in school tuberculosis (TB) screening implemented by community-level medical and health care institutions in China. The research objective was to evaluate the latent tuberculosis infection (LTBI) detection gap in school contact investigation in China.

methodsIn this cross-sectional study, school contacts were investigated by Chongqing Municipal Institute of Tuberculosis between January 2022 and April 2024 in Chongqing, China. TST, creation tuberculin skin test (C-TST), or Interferon-gamma release assays (IGRA) were conducted for immunological diagnostic methods. The LTBI detection gap among school contacts was assessed by comparing with the data implemented by community-level medical and health care institutions from 2021 to 2022.

resultsIn 6063 participants, 4233 were tested using TST, 1799 were tested using C-TST, and 31 were tested using IGRA. Seven students were confirmed to have active TB. The LTBI prevalence rate using TST and C-TST was 15.2% (95%CI, 14.1-16.3%) and 3.6% (95%CI, 2.7-4.4%) respectively. A LTBI detection gap of 10.3% was identified when comparing with TST results implemented by community-level medical and health care institutions (χ

conclusionsTB school contact investigation plays an important role in controlling TB epidemic. However, there may be a LTBI detection gap, likely due to poor quality control of TST implemented by community-level medical and health care institutions.

Indexed as

ContactLatent tuberculosisStudentsTuberculin testTuberculosis

Identifiers

PMID39833916
PMCPMC11744818

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.