Effect of different doses of ciprofol on hemodynamics induced by general anesthesia in elderly diabetic patients undergoing spinal surgery: a double-blind, randomized, controlled study.

Xiaorui Jiang, Linzhong Zhang, Jiawei Ji, Yan Jing, Meiping Li

Abstract readRandomized Controlled Trial

In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Xiaorui JiangDepartment of Anaesthesia, Second Hospital of Shanxi Medical University, Taiyuan, 030001, China.

Linzhong ZhangDepartment of Anaesthesia, Second Hospital of Shanxi Medical University, Taiyuan, 030001, China. 233423001@qq.com.

Jiawei JiDepartment of Anaesthesia, Second Hospital of Shanxi Medical University, Taiyuan, 030001, China.

Yan JingDepartment of Anaesthesia, Second Hospital of Shanxi Medical University, Taiyuan, 030001, China.

Meiping LiDepartment of Anaesthesia, Second Hospital of Shanxi Medical University, Taiyuan, 030001, China.

Funding

Beijing Health Alliance Charitable Foundation YXHA-ARP-006Department of Science and Technology of Shanxi Province 201701D121139

6 · The paper itself

Abstract

backgroundTo evaluate the safety and efficacy of different doses of ciprofol for the induction of general anesthesia in elderly patients with diabetes undergoing spinal surgery.

methodsNinety elderly diabetic patients scheduled for elective single-level posterior lumbar interbody fusion (PLIF) under general anesthesia were enrolled and randomly assigned to three groups according to the induction dose of ciprofol: group A (0.2 mg/kg), Group B (0.3 mg/kg), and Group C (0.4 mg/kg). The safety and efficacy of anesthesia induction were compared among the three groups. CASE PRESENTATION: The incidence of hypotension in Group C (46.4%) was significantly higher than that in Groups A (7.4%) and B (14.8%) (P < 0.05). The area under the time-mean arterial pressure curve (AUT

Indexed as

Anesthesia, GeneralDiabetes MellitusHemodynamicsSpinal FusionAgedCyclopropanesDose-Response Relationship, DrugDouble-Blind MethodFemaleHumansLumbar VertebraeMale(2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenolCyclopropanesCiprofolDiabetes mellitusGeneral anesthesia inductionOlder adults

Identifiers

PMID39833684

DOI10.1186/s12871-024-02881-3

PMCPMC11744958

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.