Observational studyNature human behaviour2025
Healthcare use in 12-18-year-old adolescents vaccinated against SARS-CoV-2 versus unvaccinated in a national register-based Danish cohort.
Observational study in Nature human behaviour, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04786353 (Long COVID Kids DK - Investigating Long-term Hospitalizations, GP Visits, Co-morbidities, Drug Prescriptions and Symptoms in Danish Children With Covid-19), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long COVID Kids DK - Investigating Long-term Hospitalizations, GP Visits, Co-morbidities, Drug Prescriptions and Symptoms in Danish Children With Covid-19
Who cites it
1 citing paper in PubMed.
- COVID-19 mRNA vaccines: a prospective outlook from technological innovation to clinical practice.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Healthcare use among adolescents after vaccination against SARS-CoV-2 is unknown. In a real-life register-based cohort study (trial NCT04786353), healthcare use was compared among Pfizer-BioNTech BNT162b2 COVID-19 vaccinated and unvaccinated 12-18-year-olds. First-dose-vaccinated (between 1 May and 30 September 2021) adolescents were sex and age matched 1:1 with unvaccinated adolescents. Outcomes were visits to emergency rooms, hospitalization, and visits to general practitioners and specialist practitioners. The prior event rate ratio (PERR) was applied. The study finds that boys had fewer visits to general practitioners (PERR 0.93, 95% confidence interval (CI) 0.89-0.99) after the first vaccine. Up to 56 days after the second dose, vaccinated boys had lower rates of visits to specialist practitioners (0.88, 95% CI 0.79-0.99); after 57-182 days, vaccinated girls and boys had higher rates of visits to emergency rooms (1.22, 95% CI 1.08-1.39; 1.17, 95% CI 1.07-1.31) and to general practitioners (1.17, 95% CI 1.12-1.21; 1.17, 95% CI 1.13-1.22). Furthermore, vaccinated boys had higher rates of visits to specialist practitioners (1.23, 95% CI 1.08-1.39). Estimates were close to one and do not indicate that BNT162b2 leads to a practically meaningful increase in healthcare use among vaccinated adolescents.
Indexed as
Identifiers
39833423What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.