ArticleNature medicine2025
A high-performance brain-computer interface for finger decoding and quadcopter game control in an individual with paralysis.
Article in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Restoring rapid natural bimanual typing with a neuroprosthesis after paralysis.Nature neuroscience · 2026Article
- Assistive algorithms influence neural representations in motor brain-computer interfaces.Nature communications · 2026Article
- An Event based Body Coupled Transdural Telemetry for Intracortical Brain Computer Interfaces.Communications engineering · 2026Article
- Pretraining of Embodied Recurrent Networks Bridges the Gap Between Artificial and Cortical Neural Activities.Biomimetics (Basel, Switzerland) · 2026Article
- Laminar organization of cellular microcircuits modulating human interictal epileptiform discharges.Nature neuroscience · 2026Article
- Brain-Computer Interfaces: The Dawn of a New Era in Disease Treatment.Exploration (Beijing, China) · 2026Review
- Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Intracortical brain-computer interface for navigation in virtual reality in macaque monkeys.Science advances · 2026Article
- The Compositional Encoding of Hand-Eye Coordinated Movements for Single Neurons in the Posterior Parietal Cortex.bioRxiv : the preprint server for biology · 2026Article
- Overlap in neural representations of coordinated wrist and finger movements in human motor cortex.bioRxiv : the preprint server for biology · 2026Article
- At-home movement state classification using totally implantable cortical-basal ganglia neural interface.Science advances · 2026Article
- Reliable AI Platform for Monitoring BCI Caused Brain Injury and Providing Real-Time Protection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Brain-computer interfaces: an engineering black-box swindle or a lone advance guided by deep learning.Frontiers in neuroscience · 2026Article
- A group brain-controlled method for UAVs using a hybrid paradigm of hand movements and visual evoked potentials.Frontiers in neurorobotics · 2026Article
- Spatial transcriptomics on an expanded dataset at the brain-electrode interface: exploration of variability and identification of novel biomarkers.Frontiers in neuroscience · 2026Article
- Grand challenges for systems neuroscience: perspectives and opportunities.Frontiers in systems neuroscience · 2026Article
- Long-term Intracortical Neural activity and Kinematics (LINK): An intracortical neural dataset for chronic brain-machine interfaces, neuroscience, and machine learning.Advances in neural information processing systems · 2025Article
- Toward Natural Limb Function: A New Era in Prosthetic Innovation.Annals of neurology · 2025Review
- Neuroengineering Frontiers: A Selective Review of Neural Interfaces, Brain-Machine Interactions, and Artificial Intelligence in Neurodegenerative Diseases.Applied sciences (Basel, Switzerland) · 2025Article
- Gesture encoding in human left precentral gyrus neuronal ensembles.Communications biology · 2025Article
Corrections and comments
- Update of
Authors and funding
9 authors.
Funding
Abstract
People with paralysis express unmet needs for peer support, leisure activities and sporting activities. Many within the general population rely on social media and massively multiplayer video games to address these needs. We developed a high-performance, finger-based brain-computer-interface system allowing continuous control of three independent finger groups, of which the thumb can be controlled in two dimensions, yielding a total of four degrees of freedom. The system was tested in a human research participant with tetraplegia due to spinal cord injury over sequential trials requiring fingers to reach and hold on targets, with an average acquisition rate of 76 targets per minute and completion time of 1.58 ± 0.06 seconds-comparing favorably to prior animal studies despite a twofold increase in the decoded degrees of freedom. More importantly, finger positions were then used to control a virtual quadcopter-the number-one restorative priority for the participant-using a brain-to-finger-to-computer interface to allow dexterous navigation around fixed- and random-ringed obstacle courses. The participant expressed or demonstrated a sense of enablement, recreation and social connectedness that addresses many of the unmet needs of people with paralysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.