Evidence map›Paper›PMID 39833402›Full record

ArticleScientific reports2025

Real-time trajectory imaging of alpha particles emitted from actinium-225 and its daughter radionuclides.

Seiichi Yamamoto, Masao Yoshino, Kenji Shirasaki, Kohei Nakanishi, Kei Kamada, Akira Yoshikawa, Jun Kataoka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seiichi YamamotoFaculty of Science and Engineering, Waseda University, Tokyo, Japan. s-yama@aoni.waseda.jp.
Masao YoshinoNew Industry Creation Hatchery Center, Tohoku University, Sendai, Japan.
Kenji ShirasakiInstitute of Material Research, Tohoku University, Sendai, Japan.
Kohei NakanishiNagoya University Graduate School of Medicine, Nagoya, Japan.
Kei KamadaNew Industry Creation Hatchery Center, Tohoku University, Sendai, Japan.
Akira YoshikawaNew Industry Creation Hatchery Center, Tohoku University, Sendai, Japan.
Jun KataokaFaculty of Science and Engineering, Waseda University, Tokyo, Japan.

Funding

JSPS KAKENHI 22H03019JST ERATO JPMJER2102
6 · The paper itself

Abstract

In targeted alpha-particle therapy, actinium-225 (Ac-225) has emerged as a radionuclide of potential, driving extensive efforts to develop innovative radiopharmaceuticals. High-resolution imaging of alpha particles is required for precisely detecting alpha-emitting radionuclides in cellular environments and small organs. Here, we report real-time trajectory imaging of alpha particles emitted by Ac-225 and its daughter radionuclides, utilizing an alpha particle trajectory imaging system. This system incorporates a magnification unit, a cooled electron-multiplying charge-coupled device (EM-CCD) camera, and a Ce-doped Gd

Indexed as

ActiniumAlpha ParticlesRadioisotopesRadiopharmaceuticalsAnimalsHumansMiceActiniumActinium-225RadioisotopesRadiopharmaceuticalsActinium-225Alpha particlesImaging, energy spectrumTrajectory

Identifiers

PMID39833402
PMCPMC11747257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.