Evidence map›Paper›PMID 39833368›Full record

ArticleArchives of dermatological research2025

Comparative analysis of quality of life in solid organ transplant recipients: the influence of skin cancer.

Miguel A Aristizabal, John Christiansen, Maya Makhtin, Launia J White, Michael G Heckman, Naiara S Barbosa, Catherine A Degesys, Leila Tolaymat

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Miguel A AristizabalDepartment of Dermatology, Mayo Clinic, Jacksonville, San Pablo Rd Jacksonville, Florida, 4500, 32224, USA.ORCID http://orcid.org/0000-0002-4242-0674
John ChristiansenMercer University School of Medicine, Savannah, GA, USA.
Maya MakhtinUniversity of North Florida, Jacksonville, FL, USA.
Launia J WhiteDivision of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, FL, USA.
Michael G HeckmanDivision of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, FL, USA.
Naiara S BarbosaDepartment of Dermatology, Mayo Clinic, Jacksonville, San Pablo Rd Jacksonville, Florida, 4500, 32224, USA.
Catherine A DegesysDepartment of Dermatology, Mayo Clinic, Jacksonville, San Pablo Rd Jacksonville, Florida, 4500, 32224, USA.
Leila TolaymatDepartment of Dermatology, Mayo Clinic, Jacksonville, San Pablo Rd Jacksonville, Florida, 4500, 32224, USA. Tolaymat.leila@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDermatological health-related quality of life (HRQoL) in solid organ transplant recipients (SOTRs), often affected by skin cancer, has been insufficiently explored. This study aimed to evaluate the impact of skin cancer on quality of life (QoL) in SOTRs and to compare HRQoL measures between SOTRs with and without skin cancer.

methodsThis cross-sectional study (June 2023-March 2024) assessed adult SOTRs using the Dermatology Life Quality Index (DLQI) and Skindex-29 questionnaires. For SOTRs with keratinocyte carcinoma (KC), the Basal and Squamous Cell Carcinoma Quality of Life (BaSQoL) questionnaire was also administered.

resultsA total of 150 adult SOTRs were included, with 82 having developed post-transplant skin cancer, including melanoma and KCs. DLQI scores were higher in SOTRs with skin cancer, however, the difference was not statistically significant (P ≥ 0.065). SOTRs with skin cancer had higher total Skindex-29 scores (P = 0.012) and "emotion" subscale scores (P = 0.0049), indicating a negative impact on QoL. BaSQoL scores showed a moderate negative effect on QoL, with a higher number of KCs correlating with lower QoL (P < 0.05). Female gender was associated with higher DLQI and BaSQoL diagnosis and treatment scores (P < 0.05).

conclusionsSOTRs with skin cancer had lower QoL, with greater cancer burden linked to worse outcomes. Female gender was also associated with lower QoL. Tailored management strategies are crucial for this population.

Indexed as

Basal Cell CarcinomaCarcinoma, Squamous CellMelanomaOrgan TransplantationQuality of LifeSkin NeoplasmsTransplant RecipientsAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesBasal and squamous cell carcinoma questionnaireDermatology life quality indexHealth related quality of lifeKeratinocyte carcinomaNonmelanoma skin cancerQuality of lifeSkin cancerSkindex-29Solid organ transplant recipient

Identifiers

PMID39833368

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