ArticleNature communications2025
Instantaneous self-recovery and ultra-low detection limit hydrogel electronic sensor for temporomandibular disorders intelligent diagnosis.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- A Dopamine Driven Dual-Amplifier Strategy for High Performance Bioorganic Piezoelectrics via Secondary-Structure Modulation and Synergistic Molecular Dipoles.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Nucleoside-Based Hydrogel Platform Synergizes with Photothermal Effects for Enhanced Biofilm Eradication Against Periodontitis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Smart Hydrogels in Wearable Electronics for Wound Treatments.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Predicting anterior repositioning splint efficacy in disc displacement with reduction using MRI-based texture and quantitative analysis: a retrospective study.Clinical oral investigations · 2025Article
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Authors and funding
10 authors.
Funding
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Abstract
Temporomandibular disorders (TMD) intelligent diagnosis promises to elevate clinical efficiency and facilitate timely TMD management for patients. However, development of TMD intelligent diagnostic tools with high accuracy and sensitivity presents challenges, particularly in sensing minute deformations and ensuring rapid self-recovery. Here we report a biocompatible hydrogel electronic sensor with instantaneous self-recovery (within 2.1 s) and ultra-low detection limit (0.005% strain). It could efficiently diagnose disc displacement with reduction (DDwR) with satisfactory accuracy of 90.00%, and also had a clear indication of the typical clinical manifestations of DDwR and the timing of temporomandibular joint (TMJ) clicking, with a sensitivity of up to 100% in human compared to the diagnostic criteria for TMD (DC/TMD). Furthermore, a predictive model based on waveform features achieved 84.4% accuracy and 86% sensitivity, reducing dependence on physicians. In summary, the hydrogel sensor is expected to become a radiation-free, non-invasive, practical and effective tool for future TMD diagnosis.
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Registered trials
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