Evidence map›Paper›PMID 39833005›Full record

ArticleBMJ open2025

Transfer from long-term care to acute care and risk of new permanent cognitive or physical disability among long-term care residents in Canada: protocol for a retrospective cohort study.

Christina Y Yin, Mary M Scott, Robert Talarico, Ramtin Hakimjavadi, Jackie Kierulf, Colleen Webber, Steven Hawken, Aliza Moledina, Doug Manuel, Amy Hsu and 7 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Christina Y YinBruyere Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0009-0000-5557-8633
Mary M ScottOttawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-1745-0820
Robert TalaricoInstitute for Clinical Evaluative Sciences, Ottawa, Ontario, Canada.
Ramtin HakimjavadiDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Jackie KierulfN/A, Ottawa, Ontario, Canada.
Colleen WebberBruyere Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0001-9193-5386
Steven HawkenOttawa Hospital Research Institute, Ottawa, Ontario, Canada.
Aliza MoledinaOttawa Hospital Research Institute, Ottawa, Ontario, Canada.
Doug ManuelBruyere Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0003-0912-0845
Amy HsuBruyere Research Institute, Ottawa, Ontario, Canada.
Peter TanuseputroInstitute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Celeste FungDepartment of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-1422-5759
Sharon KaasalainenSchool of Nursing, McMaster University, Hamilton, New York, Canada.
Frank MolnarOttawa Hospital Research Institute, Ottawa, Ontario, Canada.
Sandy ShamonDepartment of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada.
Daniel I McIsaacOttawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-8543-1859
Daniel KobewkaBruyere Research Institute, Ottawa, Ontario, Canada dkobewka@toh.ca.ORCID http://orcid.org/0000-0002-1812-2335

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLong-term care (LTC) residents are frequently transferred to acute care hospitals. Transfer decisions should align with residents' wishes and goals. Decision to transfer to hospital, when not aligned with the resident's wishes, can result in transfers that are harmful to residents, leaving residents in a state of disability that could be considered worse than death. We aim to examine whether transfer to an acute care hospital is associated with subsequent new onset of severe permanent physical and cognitive disability in LTC residents. METHOD AND ANALYSIS: We will conduct a retrospective cohort study of all LTC residents ≥65 admitted to LTC homes between 1 April 2013 and 31 March 2018 in Ontario, Canada. We will use health administrative data from the Continuing Care Reporting System (CCRS), National Ambulatory Care Reporting System (NACRS) and Registered Persons Databases (RPDB), which include data on emergency department visits, hospitalisations, demographic information and mortality. All participants will be followed until 31 March 2023. The exposure is any transfer from LTC to an emergency department or acute care hospital. The outcomes are (1) subsequent new permanent physical disability, (2) subsequent new permanent cognitive disability and (3) all-cause mortality. Due to the time-varying nature of the exposure and confounders, we will use an extended cause-specific Cox regression model to explore this relationship. We will fit marginal structural models (MSMs) to account for the known shortcomings of traditional regression modelling, such as collider bias. Lastly, we will use a preference-based instrumental variable approach to address unmeasured confounders. ETHICS AND DISSEMINATION: Ethics approval was obtained through Bruyère Research Institute Ethics Committee (REB#M16-23-030). Study findings will be submitted for publication in a peer-reviewed journal. Findings will be disseminated in conferences and seminars.

trial registrationOpen Science Framework (https://doi.org/10.17605/OSF.IO/JCDEY).

Indexed as

Long-Term CarePatient TransferPersons with DisabilitiesAgedAged, 80 and overEmergency Service, HospitalFemaleHumansMaleNursing HomesOntarioResearch DesignRetrospective StudiesEmergency DepartmentsEPIDEMIOLOGYHealth ServicesINTERNAL MEDICINEPALLIATIVE CARE

Identifiers

PMID39833005
PMCPMC11749797

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.