Evidence map›Paper›PMID 39832166›Full record

ArticleJMIR research protocols2025

Telehomecare Monitoring for Patients Receiving Anticancer Oral Therapy: Protocol for a Mixed Methods Evaluability Study.

Dominique Tremblay, Thomas Joly-Mischlich, Annick Dufour, Marie-Claude Battista, Djamal Berbiche, José Côté, Marco Décelles, Catherine Forget, Brigitte Guérin, Manon Larivière and 7 more

Abstract read
In one paragraph

Article in JMIR research protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Dominique TremblayNursing School, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0002-1798-5681
Thomas Joly-MischlichDepartment of Pharmacy, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0002-8745-7286
Annick DufourDepartment of Pharmacy, Centre Intégré de Santé et Services Sociaux de la Montérégie-Centre, Greenfield Park, QC, Canada.ORCID 0009-0005-2984-595X
Marie-Claude BattistaFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0001-9728-3761
Djamal BerbicheFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0002-8630-1490
José CôtéFaculty of Nursing, Université de Montréal, Montréal, QC, Canada.ORCID 0000-0002-0617-2861
Marco DécellesQuebec Cancer Foundation, Montréal, QC, Canada.ORCID 0009-0009-0917-0237
Catherine ForgetDepartment of Specialty, Surgical and Cancer Services, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0009-0002-6558-5655
Brigitte GuérinFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0002-0319-4512
Manon LarivièreDepartment of Specialty, Surgical and Cancer Services, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0009-0005-9172-5887
Frédéric LemayFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0009-0004-2000-8699
Manon LemondeFaculty of Health Sciences, Ontario Tech University, Oshawa, ON, Canada.ORCID 0000-0003-3102-1915
Éric MailletNursing School, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0002-2222-5783
Nathalie MoreauDepartment of Oncology, Centre Intégré de Santé et Services Sociaux de la Montérégie-Centre, Greenfield Park, QC, Canada.ORCID 0009-0001-4135-5364
Michel PavicDepartment of Hemato-Oncology, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0002-7057-7492
Sara SolderaCedars Cancer Centre, McGill University Health Centre, Montréal, QC, Canada.ORCID 0000-0002-2813-8111
Catherine WilhelmyCentre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0009-0009-1521-7070

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTelehomecare monitoring (TM) in patients with cancer is a complex intervention. Research shows variations in the benefits and challenges TM brings to equitable access to care, the therapeutic relationship, self-management, and practice transformation. Further investigation into these variations factors will improve implementation processes and produce effective outcomes.

objectiveThis study aims to concurrently analyze implementation and evaluate the effectiveness of TM for patients receiving anticancer oral therapy. The objectives are to (1) contextualize how and why TM is implemented according to (a) site characteristics, (b) team characteristics, and (c) characteristics of patients receiving anticancer oral therapy; (2) assess TM effectiveness for recording electronic patient-reported outcome measures (ePROMs) and patient-reported experience measures (ePREMs) according to the site, implementation process, and patient characteristics; (3) describe the acceptability and feasibility of TM from the perspectives of the people directly or indirectly involved and provide evidence-based actionable guidance in anticipation of provincewide implementation.

methodsThis type II hybrid effectiveness-implementation study uses a concurrent mixed methods design. Evaluability assessment is integrated into an emerging practice in 3 participating sites to enable the evaluation of implementation strategies on TM clinical outcomes. Quantitative data for ePROMs and ePREMs will be collected using validated oncology questionnaire. Descriptive statistics and repeated measures using multiple linear mixed models and generalized estimating equations analyses will be undertaken alongside interpretive descriptive coding of qualitative data. Qualitative data will be gathered from key informants guided by the RE-AIM (reach, efficacy, adoption, implementation, maintenance) framework and its extension, PRISM (practical robust implementation and sustainability model). The concurrent approach allows results at multiple stages of this study to be integrated iteratively. The methodological choice aims to provide real-world data that are rigorous, rapidly usable in practice, and transferable to other settings.

resultsQuestionnaires were pretested and the technological platform was codeveloped with members of the cancer care team and patients. Preparatory work was carried out to configure the TM platform and activate coordinating mechanisms between members of the cancer care team, patients, information technology experts, and the research team. A steering committee with 3 working groups was established to oversee the technological, clinical, and evaluation aspects of this study. Recruitment of patients for ePROMs started in February 2024, and data collection is expected to continue until March 2025. Interviews with members of the cancer care team began in November 2024. Full analysis should be completed by September 2025.

conclusionsThis study will clarify how, why, for whom, and under what conditions TM can complement current care models. Our evaluability assessment will help to address implementation complexities and better understand intervention-to-practice operationalization so that implementation might be adapted to contextual factors without potentially harmful or inequitable impacts on patients. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/63099.

Indexed as

Antineoplastic AgentsNeoplasmsTelemedicineAdministration, OralHumansPatient Reported Outcome MeasuresAntineoplastic Agentsanticancer oral therapyelectronic patient-reported experienceelectronic patient-reported outcomesevaluability studyimplementation.mixed methodsoncologytelehealthtelehomecare monitoringvirtual care

Identifiers

PMID39832166
PMCPMC11791446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.