Evidence map›Paper›PMID 39832112›Full record

SynthesisSpine deformity2025

Enhanced recovery after surgery for adolescent idiopathic scoliosis: a revised systematic review and meta‑analysis.

Paolo Brigato, Sergio De Salvatore, Leonardo Oggiano, Davide Palombi, Gian Mario Sangiovanni, Gianmichele Di Cosimo, Daniela Perrotta, Laura Ruzzini, Pier Francesco Costici

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Spine deformity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effect of thoracoplasty on patient-reported outcomes in adolescent idiopathic scoliosis patients undergoing posterior spinal fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paolo BrigatoResearch Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Rome, Italy.
Sergio De SalvatoreOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy. sergio.desalvatore@gmail.com.
Leonardo OggianoOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy.
Davide PalombiDepartment of Neurosurgery, Fondazione Policlinico Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168, Rome, Italy.
Gian Mario SangiovanniDepartment of Statistical Sciences, Sapienza University of Rome, Rome, Italy.
Gianmichele Di CosimoDepartment of Anesthesia and Critical Care, IRCCS, Bambino Gesù Children's Hospital, 00165, Rome, Italy.
Daniela PerrottaDepartment of Anesthesia and Critical Care, IRCCS, Bambino Gesù Children's Hospital, 00165, Rome, Italy.
Laura RuzziniOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy.
Pier Francesco CosticiOrthopedic Unit, Department of Surgery, Bambino Gesù Children's Hospital, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAdolescent idiopathic scoliosis surgery (AIS) is often associated with high costs and significant recovery challenges. Enhanced recovery after surgery (ERAS) protocols aim to improve outcomes, reducing hospital stays and complications compared to traditional (TD) pathways. This study evaluates the impact of ERAS protocols on AIS treatment.

methodsFollowing PRISMA guidelines, a systematic review identified 30 studies (n = 15,954 patients). Search terms included "ERAS," "adolescent idiopathic scoliosis," and "posterior spinal fusion." Outcomes assessed included surgical metrics, recovery milestones, complications, and pain. A meta-analysis was performed, and the risk of bias was evaluated using the MINORS score.

resultsERAS patients (n = 5582) had shorter surgical durations (- 23 min, p = 0.08) and reduced blood loss (- 126 mL, p = 0.033) compared to TD patients (n = 7916). Recovery milestones improved, including earlier ambulation (- 37.4 h, p < 0.0001), patient-controlled analgesia discontinuation (- 1.1 days, p < 0.0001), catheter removal (- 0.75 days, p < 0.001), and shorter hospital stays (- 1.7 days, p < 0.0001). Complications were lower in the ERAS group (4% vs. 8%, p = 0.0074), while wound-related complications and 30-day readmission rates were comparable. Pain scores were significantly reduced from surgery day to postoperative day 2 (p < 0.0181).

conclusionERAS protocols improve recovery and reduce complications in AIS surgery, with shorter hospital stays and enhanced patient outcomes. These findings support broader implementation and further randomized trials to evaluate long-term benefits and patient satisfaction.

Indexed as

Enhanced Recovery After SurgeryScoliosisSpinal FusionAdolescentHumansLength of StayPostoperative ComplicationsRecovery of FunctionTreatment OutcomeAccelerated dischargeAdolescent idiopathic scoliosisEnhanced recovery after surgeryPosterior spinal fusion

Identifiers

PMID39832112

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.