Evidence map›Paper›PMID 39831926›Full record

ArticleJournal of endocrinological investigation2025

Delphi consensus on the diagnostic criteria of polycystic ovary syndrome.

Fabio Facchinetti, Alessandra Gambineri, Gianluca Aimaretti, Alberto Ferlin, Antonio Simone Laganà, Paolo Moghetti, Mario Montanino Oliva, Vittorio Unfer, Annamaria Colao

Abstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Living with PCOS: A Narrative of its Biology, Diagnosis, and Evolving Treatment.Endocrine, metabolic & immune disorders drug targets · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabio FacchinettiThe Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy. facchi@unimore.it.ORCID http://orcid.org/0000-0003-4694-9564
Alessandra GambineriDivision of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0003-2242-6734
Gianluca AimarettiEndocrinology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.ORCID http://orcid.org/0000-0002-6186-0106
Alberto FerlinDepartment of Medicine, University of Padova, Padova, Italy.ORCID http://orcid.org/0000-0001-5817-8141
Antonio Simone LaganàThe Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.ORCID http://orcid.org/0000-0003-1543-2802
Paolo MoghettiUnit of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0003-3951-0297
Mario Montanino OlivaThe Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.ORCID http://orcid.org/0000-0001-8676-1465
Vittorio UnferThe Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.ORCID http://orcid.org/0000-0002-1805-3181
Annamaria ColaoThe Experts Group on Inositol in Basic and Clinical Research (EGOI), Rome, Italy.ORCID http://orcid.org/0000-0003-4049-2559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo gather the current opinion among Italian gynecologists and endocrinologists regarding the definition, diagnosis, and treatment of polycystic ovary syndrome (PCOS).

methodA Delphi survey consisting of 26 statements was designed by a nine-member panel (consisting of members from the Italian Society of Endocrinology (SIE) and the Experts Group AQon Inositol in Basic and Clinical Research and on PCOS (EGOI-PCOS)) and distributed to 102 experts in PCOS across the fields of gynecology and endocrinology. Consensus was defined as an agreement between at least 70% of responders. Participants completed three rounds of statements, ranking their level of agreement.

resultsOf the initial 26 statements, 25 reached an adequate consensus, with an overall response rate of 73%. The statements were divided into three sections: definition and current understanding, diagnosis, and treatment. Of the statements that reached consensus, near total agreement was reached in the first two sections, whereas there was a divergence of opinion in terms of optimum treatment strategy between the gynecology and endocrinology subgroups.

conclusionIt was agreed that the current clinical guidelines are inadequate for clinical and scientific practice, with most responders advocating for the inclusion of metabolic factors. Furthermore, the consensus opinion advocated for the diversification of hyperandrogenic vs. non-hyperandrogenic phenotypes. This survey gives a snapshot of the current understanding of PCOS in the Italian healthcare community.

Indexed as

Delphi TechniquePolycystic Ovary SyndromeEndocrinologyFemaleHumansItalyPractice Guidelines as TopicSurveys and QuestionnairesDelphi methodHyperandrogenismInsulin resistancePolycystic ovary syndrome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.