Evidence map›Paper›PMID 39831557›Full record

ArticleJournal of studies on alcohol and drugs2025

Typologies of Maternal Substance Use in Pregnancy: Latent Classes and Sociodemographic Correlates in a U.S. Sample.

Marina C Jenkins, Deborah B Ehrenthal, Leonelo E Bautista

Abstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Marina C JenkinsDepartment of Population, Family, and Reproductive Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Deborah B EhrenthalDepartment of Biobehavioral Health and the Social Science Research Institute, The Pennsylvania State University, University Park, Pennsylvania.
Leonelo E BautistaDepartment of Population Health Sciences, University of Wisconsin-Madison, Madison, Wisconsin.

Funding

Prenatal Opioid Exposure: Birth, health, socioeconomic, and educational outcomes of mothers and their childrenR01HD102125 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI BERGER, LAWRENCE M, EHRENTHAL, DEBORAH BETH · 2020 to 2024
$2.2M
NICHD NIH HHS R01 HD102125
6 · The paper itself

Abstract

objectiveSubstance use patterns vary considerably in the general population, yet little is known about patterns before and during pregnancy. The purpose of this study was to describe single substance and polysubstance use (PSU) before and during pregnancy among recent births in the United States and compare exposure patterns.

methodWe used data from the Pregnancy and Risk Assessment Monitoring System (PRAMS) postpartum survey for 2016-2018 to estimate the prevalence and identify patterns of substance use by participants 1 to 3 months before and during pregnancy. Data on use of cigarettes, cannabis, opioids, amphetamines, heroin, and cocaine were available for seven states. We used latent class analysis to identify patterns of substance use and tested whether participants with those patterns differed by age, income, race/ethnicity, and pre-pregnancy alcohol use. Analyses were weighted using PRAMS' state-level weights.

resultsWe studied 15,429 participants representing 384,918 live, singleton births. Approximately half (51.3%) were 20-29 years old, 42.3% were above 200% of the Federal Poverty Level, and 73.3% were non-Hispanic White. We identified seven latent classes of maternal substance use: minimal users (70.7%), pre-pregnancy cigarette users (10.5%), persistent cigarette users (6.8%), pre-pregnancy cannabis users (5.5%), broad PSU (3.6%), opioid-only users (1.9%), and persistent cigarette/opioid co-users (1.0%). Participants in these groups differed significantly by age, income, race/ethnicity, and pre-pregnancy alcohol use (

conclusionsThis novel empirical classification of single substance and PSU could help to further our understanding of the impact of PSU on perinatal health and to design interventions for maternal substance use.

Indexed as

Pregnancy ComplicationsSubstance-Related DisordersAdolescentAdultFemaleHumansLatent Class AnalysisPregnancyPrevalenceSociodemographic FactorsSocioeconomic FactorsUnited StatesYoung Adult

Identifiers

PMID39831557
PMCPMC12419505

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.