Evidence map›Paper›PMID 39831368›Full record

ArticlePain practice : the official journal of World Institute of Pain2025

The comparison of spread of methylene blue after the Pericapsular Nerve Group block and a double injection selectively targeting the articular branches to the anterior hip capsule in human cadavers.

Rachel J H Smits, Edward C T H Tan, Luuk R van den Bersselaar, Anne de Bruijn, Eva Hendriksen, Kris C P Vissers, Kim T E Olde Dubbelink, Selina E I van der Wal

Abstract readComparative Study
In one paragraph

Article in Pain practice : the official journal of World Institute of Pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rachel J H SmitsDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-1054-3087
Edward C T H TanDepartment of Surgery, Radboudumc, Nijmegen, The Netherlands.
Luuk R van den BersselaarDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.
Anne de BruijnDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.
Eva HendriksenDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.
Kris C P VissersDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.
Kim T E Olde DubbelinkDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.
Selina E I van der WalDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn this study, the spread of methylene blue was compared between an ultrasound-guided Pericapsular Nerve Group (PENG) block and a double injection technique, where the approach towards the inferomedial acetabulum was added to the latter.

methodsThe two techniques were performed in 11 fresh frozen cadavers. The spread was measured after anatomical dissection in which the supplying femoral and obturator nerves were identified. RESULTS AND

conclusionOur study demonstrates adequate staining of the iliac bone with comparable distal and medial spread in both techniques, indicating that the PENG block with a single injection is adequate in blocking the hip capsule with 10 mL local anesthetics. Staining of the femoral nerve occurred in 2/6 specimens after the PENG block, and staining of the obturator nerve in 1 specimen in each group.

Indexed as

Hip JointJoint CapsuleMethylene BlueNerve BlockAgedAged, 80 and overCadaverFemaleFemoral NerveHumansMaleMiddle AgedObturator NerveMethylene Blueanalgesiadenervationjoint painlocal anesthesiaPENG block

Identifiers

PMID39831368
PMCPMC11744490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.